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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
2007-8-8
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pubmed:abstractText |
High intensity focused ultrasound (HIFU) is an emerging non-invasive treatment modality for localized treatment of cancers. While current clinical strategies employ HIFU exclusively for thermal ablation of the target sites, biological responses associated with both thermal and mechanical damage from focused ultrasound have not been thoroughly investigated. In particular, endogenous danger signals from HIFU-damaged tumor cells may trigger the activation of dendritic cells. This response may play a critical role in a HIFU-elicited anti-tumor immune response which can be harnessed for more effective treatment.
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pubmed:grant |
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:issn |
1479-5876
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
5
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
34
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pubmed:meshHeading |
pubmed-meshheading:17625013-Animals,
pubmed-meshheading:17625013-Cell Death,
pubmed-meshheading:17625013-Cell Movement,
pubmed-meshheading:17625013-Cell Proliferation,
pubmed-meshheading:17625013-Dendritic Cells,
pubmed-meshheading:17625013-Disease Models, Animal,
pubmed-meshheading:17625013-Female,
pubmed-meshheading:17625013-High-Intensity Focused Ultrasound Ablation,
pubmed-meshheading:17625013-Immunity,
pubmed-meshheading:17625013-Lymph Nodes,
pubmed-meshheading:17625013-Mice,
pubmed-meshheading:17625013-Mice, Inbred C57BL,
pubmed-meshheading:17625013-Neoplasms,
pubmed-meshheading:17625013-Temperature
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pubmed:year |
2007
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pubmed:articleTitle |
Investigation of HIFU-induced anti-tumor immunity in a murine tumor model.
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pubmed:affiliation |
Department of Mechanical Engineering and Materials Science, Duke University, Durham, NC 27708, USA. zhenlinhu@hotmail.com
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pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Extramural
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