rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
2
|
pubmed:dateCreated |
2007-12-10
|
pubmed:abstractText |
The repair enzyme RAD18 plays a key role in the post-replication repair process in various organisms from yeast to human, and the molecular function of the RAD18 protein has been elucidated. Single nucleotide polymorphism (SNP) of arginine (Arg, CGA) or glutamine (Gln, CAA) at codon 302 is known on RAD18; however, the association between the SNP and the risk of any human cancers including non-small-cell lung cancer (NSCLC) has not been reported. We therefore investigated the relationship between the polymorphism and the development and progression of human NSCLC.
|
pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Feb
|
pubmed:issn |
1432-1335
|
pubmed:author |
pubmed-author:AoeMotoiM,
pubmed-author:DateHiroshiH,
pubmed-author:HanafusaHirokoH,
pubmed-author:ImaiKazueK,
pubmed-author:KanzakiHirotakaH,
pubmed-author:NakachiKeiK,
pubmed-author:OuchidaMamoruM,
pubmed-author:ShimizuKenjiK,
pubmed-author:SuzukiHiromitsuH,
pubmed-author:YamamotoHiromasaH,
pubmed-author:YanoMasaakiM
|
pubmed:issnType |
Electronic
|
pubmed:volume |
134
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
211-7
|
pubmed:dateRevised |
2009-3-17
|
pubmed:meshHeading |
pubmed-meshheading:17624554-Adenocarcinoma,
pubmed-meshheading:17624554-Aged,
pubmed-meshheading:17624554-Alleles,
pubmed-meshheading:17624554-Carcinoma, Large Cell,
pubmed-meshheading:17624554-Carcinoma, Non-Small-Cell Lung,
pubmed-meshheading:17624554-Carcinoma, Squamous Cell,
pubmed-meshheading:17624554-Case-Control Studies,
pubmed-meshheading:17624554-Cohort Studies,
pubmed-meshheading:17624554-DNA-Binding Proteins,
pubmed-meshheading:17624554-Female,
pubmed-meshheading:17624554-Genotype,
pubmed-meshheading:17624554-Humans,
pubmed-meshheading:17624554-Lung Neoplasms,
pubmed-meshheading:17624554-Male,
pubmed-meshheading:17624554-Polymerase Chain Reaction,
pubmed-meshheading:17624554-Polymorphism, Single Nucleotide,
pubmed-meshheading:17624554-Risk Factors
|
pubmed:year |
2008
|
pubmed:articleTitle |
The association between RAD18 Arg302Gln polymorphism and the risk of human non-small-cell lung cancer.
|
pubmed:affiliation |
Department of Molecular Genetics, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, 2-5-1 Shikata-cho, Okayama 700-8558, Japan.
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|