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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
17
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pubmed:dateCreated |
1992-2-10
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pubmed:abstractText |
In an open, randomized study, we investigated the effect of oral potassium chloride (KCl) and of potassium citrate/bicarbonate (K-cit/bic) in 42 patients with hypokalemia (less than or equal to 3.5 mmol/l). In both groups 80 mmol K+ were administered daily. The parameters examined were serum potassium concentration, acid-base status, and urinary electrolyte excretion. Parameters were evaluated on days 0, 2, 4, and 6. With KCl, [K+] increased from 3.2 +/- 0.2 (mean +/- SD) on day 0 to 3.8 +/- 0.4 mmol/l on day 2 (p less than 0.005) and 4.0 +/- 0.5 mmol/l on day 4 (p less than 0.005). On day 6 [K+] was also 4.0 +/- 0.4 mmol/l (p less than 0.005 vs day 0). With K-cit/bic, [K+] increased from 3.2 +/- 0.2 to 3.7 +/- 0.4 on day 2, 3.9 +/- 0.5 on day 4, and 4.1 +/- 0.6 mmol/l on day 6 (all p less than 0.005 vs day 0). The increase of [K+] was not different between the two groups. Blood pH on day 0 was in the normal range in both groups and did not change significantly during the study. There was a decrease of carbon dioxide partial pressure (pCO2) with KCl from 38.7 +/- 4.9 on day 0 to 36.4 +/- 3.6 on day 2 (p less than 0.05).(ABSTRACT TRUNCATED AT 250 WORDS)
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Bicarbonates,
http://linkedlifedata.com/resource/pubmed/chemical/Chlorides,
http://linkedlifedata.com/resource/pubmed/chemical/Citrates,
http://linkedlifedata.com/resource/pubmed/chemical/Citric Acid,
http://linkedlifedata.com/resource/pubmed/chemical/Potassium,
http://linkedlifedata.com/resource/pubmed/chemical/Potassium Chloride,
http://linkedlifedata.com/resource/pubmed/chemical/Sodium
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0023-2173
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
31
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pubmed:volume |
69
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
797-801
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1762385-Acid-Base Equilibrium,
pubmed-meshheading:1762385-Administration, Oral,
pubmed-meshheading:1762385-Adult,
pubmed-meshheading:1762385-Aged,
pubmed-meshheading:1762385-Aged, 80 and over,
pubmed-meshheading:1762385-Bicarbonates,
pubmed-meshheading:1762385-Chlorides,
pubmed-meshheading:1762385-Citrates,
pubmed-meshheading:1762385-Citric Acid,
pubmed-meshheading:1762385-Female,
pubmed-meshheading:1762385-Humans,
pubmed-meshheading:1762385-Hypokalemia,
pubmed-meshheading:1762385-Male,
pubmed-meshheading:1762385-Middle Aged,
pubmed-meshheading:1762385-Potassium,
pubmed-meshheading:1762385-Potassium Chloride,
pubmed-meshheading:1762385-Sodium
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pubmed:year |
1991
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pubmed:articleTitle |
Potassium substitution via the oral route: does its efficacy depend on the anion of the potassium salt?
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pubmed:affiliation |
Medizinische Universitäts-Poliklinik, Bonn.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Randomized Controlled Trial
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