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rdf:type |
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lifeskim:mentions |
umls-concept:C0001792,
umls-concept:C0003595,
umls-concept:C0011570,
umls-concept:C0017431,
umls-concept:C0024485,
umls-concept:C0205127,
umls-concept:C0392747,
umls-concept:C0497327,
umls-concept:C1274040,
umls-concept:C1527148,
umls-concept:C1801960,
umls-concept:C2603343
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pubmed:issue |
10
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pubmed:dateCreated |
2007-10-3
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pubmed:abstractText |
Several studies suggest that depression is a risk factor for development of dementia in the elderly. In a study of older depressed individuals, the authors examined both neuroimaging and genetic factors in development of dementia. The authors hypothesized that change in subcortical gray matter and white matter hyperintensity volumes would be associated with development of dementia, as would presence of an apolipoprotein E (APOE) epsilon 4 allele.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1064-7481
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
15
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
839-49
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pubmed:meshHeading |
pubmed-meshheading:17623814-Age Factors,
pubmed-meshheading:17623814-Aged,
pubmed-meshheading:17623814-Apolipoprotein E4,
pubmed-meshheading:17623814-Brain,
pubmed-meshheading:17623814-Cerebrovascular Disorders,
pubmed-meshheading:17623814-Cognition Disorders,
pubmed-meshheading:17623814-Consensus,
pubmed-meshheading:17623814-Dementia,
pubmed-meshheading:17623814-Dementia, Vascular,
pubmed-meshheading:17623814-Depressive Disorder, Major,
pubmed-meshheading:17623814-Disease Progression,
pubmed-meshheading:17623814-Female,
pubmed-meshheading:17623814-Follow-Up Studies,
pubmed-meshheading:17623814-Genotype,
pubmed-meshheading:17623814-Geriatric Assessment,
pubmed-meshheading:17623814-Humans,
pubmed-meshheading:17623814-Image Processing, Computer-Assisted,
pubmed-meshheading:17623814-Longitudinal Studies,
pubmed-meshheading:17623814-Magnetic Resonance Imaging,
pubmed-meshheading:17623814-Male,
pubmed-meshheading:17623814-Neuropsychological Tests,
pubmed-meshheading:17623814-Prevalence
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pubmed:year |
2007
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pubmed:articleTitle |
Longitudinal magnetic resonance imaging vascular changes, apolipoprotein E genotype, and development of dementia in the neurocognitive outcomes of depression in the elderly study.
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pubmed:affiliation |
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC 27710, USA. steff001@mc.duke.edu
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, N.I.H., Extramural
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