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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2007-7-10
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pubmed:abstractText |
Microarray studies of schizophrenic brains revealed decreases in the expression of myelin and oligodendrocyte-related genes. Of these genes, sex-determining region Y-box 10 (SOX10) is a major transcription factor modulating the expression of proteins involved in neurogenesis and myelination. The SOX10 gene is located on chromosome 22q13.1, a region repeatedly reported to show positive signals in linkage studies on schizophrenia.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0955-8829
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pubmed:author |
pubmed-author:AoyamaNagisaN,
pubmed-author:BrankoAleksicA,
pubmed-author:IkedaMasashiM,
pubmed-author:InadaToshiyaT,
pubmed-author:IshiharaRyokoR,
pubmed-author:IwataNakaoN,
pubmed-author:JiXiaofeiX,
pubmed-author:KinoshitaYokoY,
pubmed-author:KitajimaTsuyoshiT,
pubmed-author:MaenoNobuhisaN,
pubmed-author:MiuraHidekiH,
pubmed-author:OzakiNorioN,
pubmed-author:SaitoShinichiS,
pubmed-author:SuzukiTatsuyoT,
pubmed-author:TakahashiNagahideN,
pubmed-author:YamanouchiYoshioY
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pubmed:issnType |
Print
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pubmed:volume |
17
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
227-31
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:17621166-Adult,
pubmed-meshheading:17621166-Aged,
pubmed-meshheading:17621166-Chromosome Mapping,
pubmed-meshheading:17621166-Chromosomes, Human, Pair 22,
pubmed-meshheading:17621166-DNA Primers,
pubmed-meshheading:17621166-DNA-Binding Proteins,
pubmed-meshheading:17621166-Female,
pubmed-meshheading:17621166-Genetic Predisposition to Disease,
pubmed-meshheading:17621166-Genotype,
pubmed-meshheading:17621166-High Mobility Group Proteins,
pubmed-meshheading:17621166-Humans,
pubmed-meshheading:17621166-Japan,
pubmed-meshheading:17621166-Male,
pubmed-meshheading:17621166-Middle Aged,
pubmed-meshheading:17621166-Mutation,
pubmed-meshheading:17621166-Oligonucleotide Array Sequence Analysis,
pubmed-meshheading:17621166-Reference Values,
pubmed-meshheading:17621166-SOXE Transcription Factors,
pubmed-meshheading:17621166-Schizophrenia,
pubmed-meshheading:17621166-Transcription Factors
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pubmed:year |
2007
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pubmed:articleTitle |
Association of SOX10 with schizophrenia in the Japanese population.
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pubmed:affiliation |
Department of Psychiatry, Nagoya University Graduate School of Medicine, Nagoya, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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