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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
8
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pubmed:dateCreated |
2007-7-10
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pubmed:abstractText |
Angiotensin II plays a crucial role in the induction of oxidative stress and the pathogenesis of cardiovascular and renal diseases, and the beneficial mechanisms of angiotensin II receptor 1 blockers (ARBs) are multifactorial. We investigated the receptor-independent protective role of an ARB using primary-cultured mesangial cells from angiotensin II receptor 1 knockout or wild-type mice and a highly lipophilic ARB, telmisartan.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Angiotensin II Type 1 Receptor...,
http://linkedlifedata.com/resource/pubmed/chemical/Benzimidazoles,
http://linkedlifedata.com/resource/pubmed/chemical/Benzoates,
http://linkedlifedata.com/resource/pubmed/chemical/DNA Primers,
http://linkedlifedata.com/resource/pubmed/chemical/Free Radical Scavengers,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/Reactive Oxygen Species,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Angiotensin,
http://linkedlifedata.com/resource/pubmed/chemical/telmisartan
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0263-6352
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
25
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1643-9
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pubmed:meshHeading |
pubmed-meshheading:17620961-Angiotensin II Type 1 Receptor Blockers,
pubmed-meshheading:17620961-Animals,
pubmed-meshheading:17620961-Base Sequence,
pubmed-meshheading:17620961-Benzimidazoles,
pubmed-meshheading:17620961-Benzoates,
pubmed-meshheading:17620961-DNA Primers,
pubmed-meshheading:17620961-Dose-Response Relationship, Drug,
pubmed-meshheading:17620961-Free Radical Scavengers,
pubmed-meshheading:17620961-Mice,
pubmed-meshheading:17620961-Mice, Knockout,
pubmed-meshheading:17620961-Oxidative Stress,
pubmed-meshheading:17620961-Polymerase Chain Reaction,
pubmed-meshheading:17620961-RNA, Messenger,
pubmed-meshheading:17620961-Reactive Oxygen Species,
pubmed-meshheading:17620961-Receptors, Angiotensin,
pubmed-meshheading:17620961-Up-Regulation
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pubmed:year |
2007
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pubmed:articleTitle |
Receptor-independent intracellular radical scavenging activity of an angiotensin II receptor blocker.
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pubmed:affiliation |
Division of Nephrology and Endocrinology, University of Tokyo School of Medicine, Tokyo, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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