Linked Life Data

17620362

Source:http://linkedlifedata.com/resource/pubmed/id/17620362

Statements in which the resource exists.
SubjectPredicateObjectContext
pubmed-article:17620362rdf:typepubmed:Citationlld:pubmed
pubmed-article:17620362lifeskim:mentionsumls-concept:C0007634lld:lifeskim
pubmed-article:17620362lifeskim:mentionsumls-concept:C0227264lld:lifeskim
pubmed-article:17620362lifeskim:mentionsumls-concept:C0011306lld:lifeskim
pubmed-article:17620362lifeskim:mentionsumls-concept:C0040845lld:lifeskim
pubmed-article:17620362lifeskim:mentionsumls-concept:C0033414lld:lifeskim
pubmed-article:17620362lifeskim:mentionsumls-concept:C1416467lld:lifeskim
pubmed-article:17620362lifeskim:mentionsumls-concept:C0079411lld:lifeskim
pubmed-article:17620362lifeskim:mentionsumls-concept:C1515568lld:lifeskim
pubmed-article:17620362pubmed:issue8lld:pubmed
pubmed-article:17620362pubmed:dateCreated2007-8-7lld:pubmed
pubmed-article:17620362pubmed:abstractTextTo maintain immune homeostasis, the intestinal immune system has evolved redundant regulatory strategies. In this regard, the gut is home to a large number of regulatory T (T reg) cells, including the Foxp3(+) T reg cell. Therefore, we hypothesized that the gut environment preferentially supports extrathymic T reg cell development. We show that peripheral conversion of CD4(+) T cells to T reg cells occurs primarily in gut-associated lymphoid tissue (GALT) after oral exposure to antigen and in a lymphopenic environment. Dendritic cells (DCs) purified from the lamina propria (Lp; LpDCs) of the small intestine were found to promote a high level of T reg cell conversion relative to lymphoid organ-derived DCs. This enhanced conversion by LpDCs was dependent on TGF-beta and retinoic acid (RA), which is a vitamin A metabolite highly expressed in GALT. Together, these data demonstrate that the intestinal immune system has evolved a self-contained strategy to promote T reg cell neoconversion.lld:pubmed
pubmed-article:17620362pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:17620362pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:17620362pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:17620362pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:17620362pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:17620362pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:17620362pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:17620362pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:17620362pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:17620362pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:17620362pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:17620362pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:17620362pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:17620362pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:17620362pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:17620362pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:17620362pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:17620362pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:17620362pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:17620362pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:17620362pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:17620362pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:17620362pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:17620362pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:17620362pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:17620362pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:17620362pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:17620362pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:17620362pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:17620362pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:17620362pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:17620362pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:17620362pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:17620362pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:17620362pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:17620362pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:17620362pubmed:languageenglld:pubmed
pubmed-article:17620362pubmed:journalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:17620362pubmed:citationSubsetIMlld:pubmed
pubmed-article:17620362pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:17620362pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:17620362pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:17620362pubmed:statusMEDLINElld:pubmed
pubmed-article:17620362pubmed:monthAuglld:pubmed
pubmed-article:17620362pubmed:issn0022-1007lld:pubmed
pubmed-article:17620362pubmed:authorpubmed-author:OukkaMohamedMlld:pubmed
pubmed-article:17620362pubmed:authorpubmed-author:SunCheng-Ming...lld:pubmed
pubmed-article:17620362pubmed:authorpubmed-author:BelkaidYasmin...lld:pubmed
pubmed-article:17620362pubmed:authorpubmed-author:HallJason AJAlld:pubmed
pubmed-article:17620362pubmed:authorpubmed-author:MoraJ...lld:pubmed
pubmed-article:17620362pubmed:authorpubmed-author:BouladouxNico...lld:pubmed
pubmed-article:17620362pubmed:authorpubmed-author:BlankRebecca...lld:pubmed
pubmed-article:17620362pubmed:issnTypePrintlld:pubmed
pubmed-article:17620362pubmed:day6lld:pubmed
pubmed-article:17620362pubmed:volume204lld:pubmed
pubmed-article:17620362pubmed:ownerNLMlld:pubmed
pubmed-article:17620362pubmed:authorsCompleteYlld:pubmed
pubmed-article:17620362pubmed:pagination1775-85lld:pubmed
pubmed-article:17620362pubmed:dateRevised2009-11-18lld:pubmed
pubmed-article:17620362pubmed:meshHeadingpubmed-meshheading:17620362...lld:pubmed
pubmed-article:17620362pubmed:meshHeadingpubmed-meshheading:17620362...lld:pubmed
pubmed-article:17620362pubmed:meshHeadingpubmed-meshheading:17620362...lld:pubmed
pubmed-article:17620362pubmed:meshHeadingpubmed-meshheading:17620362...lld:pubmed
pubmed-article:17620362pubmed:meshHeadingpubmed-meshheading:17620362...lld:pubmed
pubmed-article:17620362pubmed:meshHeadingpubmed-meshheading:17620362...lld:pubmed
pubmed-article:17620362pubmed:meshHeadingpubmed-meshheading:17620362...lld:pubmed
pubmed-article:17620362pubmed:meshHeadingpubmed-meshheading:17620362...lld:pubmed
pubmed-article:17620362pubmed:meshHeadingpubmed-meshheading:17620362...lld:pubmed
pubmed-article:17620362pubmed:meshHeadingpubmed-meshheading:17620362...lld:pubmed
pubmed-article:17620362pubmed:meshHeadingpubmed-meshheading:17620362...lld:pubmed
pubmed-article:17620362pubmed:meshHeadingpubmed-meshheading:17620362...lld:pubmed
pubmed-article:17620362pubmed:meshHeadingpubmed-meshheading:17620362...lld:pubmed
pubmed-article:17620362pubmed:meshHeadingpubmed-meshheading:17620362...lld:pubmed
pubmed-article:17620362pubmed:meshHeadingpubmed-meshheading:17620362...lld:pubmed
pubmed-article:17620362pubmed:year2007lld:pubmed
pubmed-article:17620362pubmed:articleTitleSmall intestine lamina propria dendritic cells promote de novo generation of Foxp3 T reg cells via retinoic acid.lld:pubmed
pubmed-article:17620362pubmed:affiliationMucosal Immunology Unit, Laboratory of Parasitic Diseases, National Institute for Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.lld:pubmed
pubmed-article:17620362pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:17620362pubmed:publicationTypeResearch Support, N.I.H., Intramurallld:pubmed
entrez-gene:20371entrezgene:pubmedpubmed-article:17620362lld:entrezgene
http://linkedlifedata.com/r...entrezgene:pubmedpubmed-article:17620362lld:entrezgene
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17620362lld:pubmed
More...