|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
2
|
|
pubmed:dateCreated |
2008-11-4
|
|
pubmed:abstractText |
The binding of platelet glycoprotein (GP) Ib-IX-V receptor complex to subendothelial collagen via von Willebrand factor is the initial step of the formation of platelet thrombi following atherosclerotic plaque rupture. Platelet GPIV binds to collagen and/or thrombospondin and further activates platelets. Genetic variation in these proteins could associate with platelet aggregability and the risk of myocardial infarction (MI).
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Oct
|
|
pubmed:issn |
0929-5305
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
26
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
91-6
|
|
pubmed:dateRevised |
2010-12-8
|
|
pubmed:meshHeading |
pubmed-meshheading:17619827-Adult,
pubmed-meshheading:17619827-Aged,
pubmed-meshheading:17619827-Antigens, CD36,
pubmed-meshheading:17619827-Coronary Artery Disease,
pubmed-meshheading:17619827-Coronary Stenosis,
pubmed-meshheading:17619827-Death, Sudden, Cardiac,
pubmed-meshheading:17619827-Finland,
pubmed-meshheading:17619827-Gene Frequency,
pubmed-meshheading:17619827-Genetic Predisposition to Disease,
pubmed-meshheading:17619827-Haplotypes,
pubmed-meshheading:17619827-Humans,
pubmed-meshheading:17619827-Male,
pubmed-meshheading:17619827-Membrane Glycoproteins,
pubmed-meshheading:17619827-Membrane Proteins,
pubmed-meshheading:17619827-Middle Aged,
pubmed-meshheading:17619827-Myocardial Infarction,
pubmed-meshheading:17619827-Odds Ratio,
pubmed-meshheading:17619827-Platelet Aggregation,
pubmed-meshheading:17619827-Polymorphism, Genetic,
pubmed-meshheading:17619827-Prospective Studies,
pubmed-meshheading:17619827-Risk Assessment,
pubmed-meshheading:17619827-von Willebrand Factor
|
|
pubmed:year |
2008
|
|
pubmed:articleTitle |
Platelet GPIbalpha, GPIV and vWF polymorphisms and fatal pre-hospital MI among middle-aged men.
|
|
pubmed:affiliation |
Medical School/B-building, University of Tampere, Tampere, 33014, Finland.
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
