| pubmed-article:17613522 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:17613522 | lifeskim:mentions | umls-concept:C0012854 | lld:lifeskim |
| pubmed-article:17613522 | lifeskim:mentions | umls-concept:C0010715 | lld:lifeskim |
| pubmed-article:17613522 | lifeskim:mentions | umls-concept:C1519249 | lld:lifeskim |
| pubmed-article:17613522 | lifeskim:mentions | umls-concept:C0599894 | lld:lifeskim |
| pubmed-article:17613522 | lifeskim:mentions | umls-concept:C0680948 | lld:lifeskim |
| pubmed-article:17613522 | lifeskim:mentions | umls-concept:C1710236 | lld:lifeskim |
| pubmed-article:17613522 | lifeskim:mentions | umls-concept:C1521840 | lld:lifeskim |
| pubmed-article:17613522 | pubmed:issue | 35 | lld:pubmed |
| pubmed-article:17613522 | pubmed:dateCreated | 2007-8-27 | lld:pubmed |
| pubmed-article:17613522 | pubmed:abstractText | The molecular features that allow activation-induced cytidine deaminase (AID) to target Ig and certain non-Ig genes are not understood, although transcription has been implicated as one important parameter. We explored this issue by testing the mutability of a non-Ig transcription cassette in Ig and non-Ig loci of the chicken B cell line DT40. The cassette did not act as a stable long term mutation target but was able to be mutated in an AID-dependent manner for a limited time post-integration. This indicates that newly integrated DNA has molecular characteristics that render it susceptible to modification by AID, with implications for how targeting and mis-targeting of AID occurs. | lld:pubmed |
| pubmed-article:17613522 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17613522 | pubmed:language | eng | lld:pubmed |
| pubmed-article:17613522 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17613522 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:17613522 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17613522 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17613522 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17613522 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:17613522 | pubmed:month | Aug | lld:pubmed |
| pubmed-article:17613522 | pubmed:issn | 0021-9258 | lld:pubmed |
| pubmed-article:17613522 | pubmed:author | pubmed-author:FugmannSebast... | lld:pubmed |
| pubmed-article:17613522 | pubmed:author | pubmed-author:SchatzDavid... | lld:pubmed |
| pubmed-article:17613522 | pubmed:author | pubmed-author:YangShu... | lld:pubmed |
| pubmed-article:17613522 | pubmed:author | pubmed-author:GramlichHilla... | lld:pubmed |
| pubmed-article:17613522 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:17613522 | pubmed:day | 31 | lld:pubmed |
| pubmed-article:17613522 | pubmed:volume | 282 | lld:pubmed |
| pubmed-article:17613522 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:17613522 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:17613522 | pubmed:pagination | 25308-13 | lld:pubmed |
| pubmed-article:17613522 | pubmed:dateRevised | 2007-12-3 | lld:pubmed |
| pubmed-article:17613522 | pubmed:meshHeading | pubmed-meshheading:17613522... | lld:pubmed |
| pubmed-article:17613522 | pubmed:meshHeading | pubmed-meshheading:17613522... | lld:pubmed |
| pubmed-article:17613522 | pubmed:meshHeading | pubmed-meshheading:17613522... | lld:pubmed |
| pubmed-article:17613522 | pubmed:meshHeading | pubmed-meshheading:17613522... | lld:pubmed |
| pubmed-article:17613522 | pubmed:meshHeading | pubmed-meshheading:17613522... | lld:pubmed |
| pubmed-article:17613522 | pubmed:meshHeading | pubmed-meshheading:17613522... | lld:pubmed |
| pubmed-article:17613522 | pubmed:meshHeading | pubmed-meshheading:17613522... | lld:pubmed |
| pubmed-article:17613522 | pubmed:meshHeading | pubmed-meshheading:17613522... | lld:pubmed |
| pubmed-article:17613522 | pubmed:meshHeading | pubmed-meshheading:17613522... | lld:pubmed |
| pubmed-article:17613522 | pubmed:meshHeading | pubmed-meshheading:17613522... | lld:pubmed |
| pubmed-article:17613522 | pubmed:meshHeading | pubmed-meshheading:17613522... | lld:pubmed |
| pubmed-article:17613522 | pubmed:meshHeading | pubmed-meshheading:17613522... | lld:pubmed |
| pubmed-article:17613522 | pubmed:year | 2007 | lld:pubmed |
| pubmed-article:17613522 | pubmed:articleTitle | Activation-induced cytidine deaminase-mediated sequence diversification is transiently targeted to newly integrated DNA substrates. | lld:pubmed |
| pubmed-article:17613522 | pubmed:affiliation | Department of Immunobiology, Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, Connecticut 06520-8011, USA. | lld:pubmed |
| pubmed-article:17613522 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:17613522 | pubmed:publicationType | Research Support, U.S. Gov't, Non-P.H.S. | lld:pubmed |
| pubmed-article:17613522 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| pubmed-article:17613522 | pubmed:publicationType | Research Support, N.I.H., Extramural | lld:pubmed |
