Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2007-10-23
pubmed:abstractText
Gold nanowires were prepared by an electrodeposition strategy using nanopore polycarbonate (PC) membrane, with the average diameter of the nanowires about 250 nm and length about 10 microm. The nanowires prepared were dispersed into chitosan (CHIT) solution and stably immobilized onto glassy carbon electrode (GCE) surface. The electrochemical behavior of gold nanowire modified electrode and its application to the electrocatalytic reduction of hydrogen peroxide (H(2)O(2)) were investigated. The modified electrode allows low potential detection of hydrogen peroxide with high sensitivity and fast response time. Moreover, the good biocompatibility of nanometer-sized gold, the vast surface area of the nanowire-structure make it ideal for adsorption of enzymes for the fabrication of biosensors. Glucose oxidase was adsorbed onto the nanowire surface to fabricate glucose biosensor as an application example. The detection of glucose was performed in phosphate buffer (pH 6.98) at -0.2 V. The resulting glucose biosensor exhibited sensitive response, with a short response time (<8 s), a linear range of 10(-5)-2 x 10(-2) M and detection limit of 5 x 10(-6) M.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
1567-5394
pubmed:author
pubmed:issnType
Print
pubmed:volume
71
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
211-6
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
Enzyme-functionalized gold nanowires for the fabrication of biosensors.
pubmed:affiliation
Chemistry and Chemical Engineering College, State Key Laboratory of Chemo/Biosensing and Chemometrics, Hunan University, Changsha 410082, PR China.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't