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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
2007-7-20
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pubmed:abstractText |
The zebrafish (Danio rerio) is an important vertebrate model organism system for biomedical research. The syntenic conservation between the zebrafish and human genome allows one to investigate the function of human genes using the zebrafish model. To facilitate analysis of the zebrafish genome, genetic maps have been constructed and sequence annotation of a reference zebrafish genome is ongoing. However, the duplicative nature of teleost genomes, including the zebrafish, complicates accurate assembly and annotation of a representative genome sequence. Cytogenetic approaches provide "anchors" that can be integrated with accumulating genomic data.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/17597531-10207156,
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http://linkedlifedata.com/resource/pubmed/commentcorrection/17597531-9831563
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:issn |
1471-2164
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pubmed:author |
pubmed-author:AdeniyiAdeolaA,
pubmed-author:BanerjeeRubyR,
pubmed-author:CarterNigel PNP,
pubmed-author:ChiJianxiangJ,
pubmed-author:DallaireStephanieS,
pubmed-author:FreemanJennifer LJL,
pubmed-author:HumphraySeanS,
pubmed-author:LeeCharlesC,
pubmed-author:MaguireSean FSF,
pubmed-author:NgBee LingBL,
pubmed-author:RogersJaneJ,
pubmed-author:ScottCarol ECE,
pubmed-author:YangFengtangF,
pubmed-author:ZepedaCinthyaC,
pubmed-author:ZhouYiY,
pubmed-author:ZonLeonard ILI
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pubmed:issnType |
Electronic
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pubmed:volume |
8
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
195
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:17597531-Animals,
pubmed-meshheading:17597531-Chromosome Mapping,
pubmed-meshheading:17597531-Chromosomes, Artificial, Bacterial,
pubmed-meshheading:17597531-Cytogenetics,
pubmed-meshheading:17597531-Flow Cytometry,
pubmed-meshheading:17597531-Genetic Techniques,
pubmed-meshheading:17597531-Genome,
pubmed-meshheading:17597531-Genomic Library,
pubmed-meshheading:17597531-Genomics,
pubmed-meshheading:17597531-In Situ Hybridization, Fluorescence,
pubmed-meshheading:17597531-Microscopy, Fluorescence,
pubmed-meshheading:17597531-Models, Genetic,
pubmed-meshheading:17597531-Telomere,
pubmed-meshheading:17597531-Zebrafish
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pubmed:year |
2007
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pubmed:articleTitle |
Definition of the zebrafish genome using flow cytometry and cytogenetic mapping.
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pubmed:affiliation |
Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA. jfreeman7@partners.org <jfreeman7@partners.org>
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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