Source:http://linkedlifedata.com/resource/pubmed/id/17596266
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
2007-8-31
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pubmed:abstractText |
Studies associate alcohol consumption, cigarette smoking, and body size with the risk of overall or subtype lymphoma. Current data come mostly from case-control studies or prospective studies with few cases. In the prospective National Institutes of Health-former American Association of Retired Persons (NIH-AARP) Diet and Health Study, the authors assessed the above lifestyle factors via baseline questionnaire among 285,079 men and 188,905 women aged 50-71 years and ascertained histologically confirmed Hodgkin's lymphoma (n = 58) and non-Hodgkin's lymphoma (n = 1,381) cases through linkage with cancer registries from 1995 to 2000. Compared with nondrinkers, alcohol consumers had a lower risk for non-Hodgkin's lymphoma overall (for >28 drinks/week: adjusted relative risk (RR) = 0.77, 95% confidence interval (CI): 0.59, 1.00; p(trend) among drinkers = 0.02) and for its main subtypes. Compared with never smokers, current smokers and recent quitters (<or=4 years ago) had higher risk of Hodgkin's lymphoma (RR = 2.25, 95% CI: 1.04, 4.89; RR = 4.20, 95% CI: 1.94, 9.09, respectively), whereas current or former smokers had lower risk of follicular non-Hodgkin's lymphoma (RR = 0.67, 95% CI: 0.52, 0.86). Severe obesity (body mass index of >or=35: RR = 1.29, 95% CI: 1.02, 1.64) and taller height (RR = 1.19, 95% CI: 1.03, 1.38) were associated moderately with non-Hodgkin's lymphoma. These findings add to the evidence that lifestyle factors and relevant anthropometric characteristics play a role in lymphoma etiology.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0002-9262
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pubmed:author |
pubmed-author:BarisDalsuD,
pubmed-author:CarrollLeslieL,
pubmed-author:HartgePatriciaP,
pubmed-author:KipnisVictorV,
pubmed-author:LeitzmannMichaelM,
pubmed-author:LimUnheeU,
pubmed-author:MortonLindsay MLM,
pubmed-author:MouwTraciT,
pubmed-author:SchatzkinArthurA,
pubmed-author:Stolzenberg-SolomonRachaelR,
pubmed-author:SubarAmy FAF
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pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
166
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
697-708
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pubmed:meshHeading |
pubmed-meshheading:17596266-Aged,
pubmed-meshheading:17596266-Alcohol Drinking,
pubmed-meshheading:17596266-Anthropometry,
pubmed-meshheading:17596266-Body Size,
pubmed-meshheading:17596266-Chi-Square Distribution,
pubmed-meshheading:17596266-Female,
pubmed-meshheading:17596266-Hodgkin Disease,
pubmed-meshheading:17596266-Humans,
pubmed-meshheading:17596266-Incidence,
pubmed-meshheading:17596266-Lymphoma, Non-Hodgkin,
pubmed-meshheading:17596266-Male,
pubmed-meshheading:17596266-Middle Aged,
pubmed-meshheading:17596266-Proportional Hazards Models,
pubmed-meshheading:17596266-Prospective Studies,
pubmed-meshheading:17596266-Questionnaires,
pubmed-meshheading:17596266-SEER Program,
pubmed-meshheading:17596266-Smoking,
pubmed-meshheading:17596266-United States
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pubmed:year |
2007
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pubmed:articleTitle |
Alcohol, smoking, and body size in relation to incident Hodgkin's and non-Hodgkin's lymphoma risk.
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pubmed:affiliation |
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD 20852, USA. limu@mail.nih.gov
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pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Intramural
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