Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
2007-7-31
pubmed:abstractText
Plasmid DNA vectors offer the potential of safe gene therapy avoiding viral vector-mediated toxicity and immunogenicity. As plasmid DNA is bacterial in origin, presence of bacterial lipopolysaccharide (LPS) or unmethylated CpG dinucleotides may stimulate host innate immunity.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
1099-498X
pubmed:author
pubmed:copyrightInfo
Copyright 2007 John Wiley & Sons, Ltd.
pubmed:issnType
Print
pubmed:volume
9
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
703-14
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed-meshheading:17595049-Animals, pubmed-meshheading:17595049-CD8-Positive T-Lymphocytes, pubmed-meshheading:17595049-CpG Islands, pubmed-meshheading:17595049-Dendritic Cells, pubmed-meshheading:17595049-Endotoxins, pubmed-meshheading:17595049-Fluorescent Antibody Technique, pubmed-meshheading:17595049-Gene Therapy, pubmed-meshheading:17595049-Green Fluorescent Proteins, pubmed-meshheading:17595049-Insulin, pubmed-meshheading:17595049-Interleukin-12, pubmed-meshheading:17595049-Lipopolysaccharides, pubmed-meshheading:17595049-Macrophages, pubmed-meshheading:17595049-Mice, pubmed-meshheading:17595049-Monocytes, pubmed-meshheading:17595049-Muscles, pubmed-meshheading:17595049-Oligodeoxyribonucleotides, pubmed-meshheading:17595049-Plasmids, pubmed-meshheading:17595049-Rats, pubmed-meshheading:17595049-Rats, Wistar, pubmed-meshheading:17595049-Transgenes, pubmed-meshheading:17595049-beta-Galactosidase
pubmed:year
2007
pubmed:articleTitle
In vitro and in vivo evaluation of intrinsic immunogenicity of reporter and insulin gene therapy plasmids.
pubmed:affiliation
Diabetes Research Group, Institute of Cell and Molecular Biosciences, University of Newcastle upon Tyne, Framlington Place, Newcastle upon Tyne NE2 4HH, UK.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't, Evaluation Studies