Source:http://linkedlifedata.com/resource/pubmed/id/17593905
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
9
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pubmed:dateCreated |
2007-8-28
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pubmed:abstractText |
Obesity is associated with a chronic low-grade inflammation and an increased abundance of macrophages in adipose tissue. Adipose tissue macrophages (ATMs) are assumed to interfere with adipocyte function leading to insulin resistance, thereby contributing to the pathogenesis of type 2 diabetes mellitus. Macrophages exist in separate types of differentiation, but the nature of ATMs is largely unknown.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0307-0565
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
31
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1420-8
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pubmed:dateRevised |
2009-9-15
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pubmed:meshHeading |
pubmed-meshheading:17593905-Adipose Tissue,
pubmed-meshheading:17593905-Diabetes Mellitus, Type 2,
pubmed-meshheading:17593905-Female,
pubmed-meshheading:17593905-Humans,
pubmed-meshheading:17593905-Inflammation Mediators,
pubmed-meshheading:17593905-Insulin Resistance,
pubmed-meshheading:17593905-Interleukin 1 Receptor Antagonist Protein,
pubmed-meshheading:17593905-Interleukin-10,
pubmed-meshheading:17593905-Macrophages,
pubmed-meshheading:17593905-Male,
pubmed-meshheading:17593905-Obesity,
pubmed-meshheading:17593905-Phenotype
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pubmed:year |
2007
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pubmed:articleTitle |
Human adipose tissue macrophages are of an anti-inflammatory phenotype but capable of excessive pro-inflammatory mediator production.
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pubmed:affiliation |
Clinical Division of Endocrinology and Metabolism, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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