| pubmed-article:17593860 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:17593860 | lifeskim:mentions | umls-concept:C0003873 | lld:lifeskim |
| pubmed-article:17593860 | lifeskim:mentions | umls-concept:C0032659 | lld:lifeskim |
| pubmed-article:17593860 | lifeskim:mentions | umls-concept:C0152035 | lld:lifeskim |
| pubmed-article:17593860 | lifeskim:mentions | umls-concept:C0021753 | lld:lifeskim |
| pubmed-article:17593860 | lifeskim:mentions | umls-concept:C1522384 | lld:lifeskim |
| pubmed-article:17593860 | lifeskim:mentions | umls-concept:C0017431 | lld:lifeskim |
| pubmed-article:17593860 | lifeskim:mentions | umls-concept:C0524899 | lld:lifeskim |
| pubmed-article:17593860 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:17593860 | pubmed:dateCreated | 2007-6-27 | lld:pubmed |
| pubmed-article:17593860 | pubmed:abstractText | Polymorphism (variable number of tandem repeats) in the second intron of the interleukin-1 receptor antagonist (IL-1Ra) gene and two single nucleotide polymorphisms at positions -511 and +3954 of the IL-1beta gene may be associated with an increased risk of rheumatoid arthritis (RA). This study used sex stratification to investigate a correlation of the three genetic polymorphisms with the risk of RA, on patients with RA and healthy controls. Polymerase chain reaction (PCR) and polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) were performed. The frequencies of the IL-1beta+3954 allele and genotype in female patients were significantly different compared with the controls; but in males, only the frequency of the IL-1beta+3954 allele was different. The frequency of the IL-1RN genotype in patients was not statistically different compared with the controls; however, the frequency of IL-1RN allele in female patients was different. The association of the three polymorphisms with the susceptibility to RA appears to be significantly affected by gender. | lld:pubmed |
| pubmed-article:17593860 | pubmed:language | eng | lld:pubmed |
| pubmed-article:17593860 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17593860 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:17593860 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:17593860 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17593860 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:17593860 | pubmed:issn | 0300-0605 | lld:pubmed |
| pubmed-article:17593860 | pubmed:author | pubmed-author:ChenY RYR | lld:pubmed |
| pubmed-article:17593860 | pubmed:author | pubmed-author:MoyR MRM | lld:pubmed |
| pubmed-article:17593860 | pubmed:author | pubmed-author:WangZ PZP | lld:pubmed |
| pubmed-article:17593860 | pubmed:author | pubmed-author:YooC ICI | lld:pubmed |
| pubmed-article:17593860 | pubmed:author | pubmed-author:RYER MRM | lld:pubmed |
| pubmed-article:17593860 | pubmed:author | pubmed-author:IOTT | lld:pubmed |
| pubmed-article:17593860 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:17593860 | pubmed:volume | 35 | lld:pubmed |
| pubmed-article:17593860 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:17593860 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:17593860 | pubmed:pagination | 323-8 | lld:pubmed |
| pubmed-article:17593860 | pubmed:dateRevised | 2007-9-20 | lld:pubmed |
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| pubmed-article:17593860 | pubmed:meshHeading | pubmed-meshheading:17593860... | lld:pubmed |
| pubmed-article:17593860 | pubmed:articleTitle | Sex influences on the penetrance of IL-1beta and IL-1RN genotypes for rheumatoid arthritis in the Chinese population. | lld:pubmed |
| pubmed-article:17593860 | pubmed:affiliation | School of Life Sciences, Lanzhou University, Lanzhou City, China. | lld:pubmed |
| pubmed-article:17593860 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:17593860 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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