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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3A
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pubmed:dateCreated |
2007-6-27
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pubmed:abstractText |
Striking similarities between stem cells and cancer cells have led to the concept of the existence of a cancer stem cell, a concept that has since been documented in many tumours including breast, brain and prostate tumours. Teratocarcinomas are malignant tumours occurring predominantly in the testes composed of undifferentiated stem cells and mature tissues. Cancer stemness was studied using the teratocarcinoma model of tumourigenesis.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
0250-7005
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
27
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1319-24
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:17593625-Animals,
pubmed-meshheading:17593625-Cell Line, Tumor,
pubmed-meshheading:17593625-Embryonal Carcinoma Stem Cells,
pubmed-meshheading:17593625-Embryonic Stem Cells,
pubmed-meshheading:17593625-Gene Expression Profiling,
pubmed-meshheading:17593625-Gene Expression Regulation, Developmental,
pubmed-meshheading:17593625-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:17593625-Mice,
pubmed-meshheading:17593625-Neoplastic Stem Cells,
pubmed-meshheading:17593625-Oligonucleotide Array Sequence Analysis,
pubmed-meshheading:17593625-RNA, Messenger,
pubmed-meshheading:17593625-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:17593625-Teratocarcinoma,
pubmed-meshheading:17593625-Transcription, Genetic
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pubmed:articleTitle |
Global mRNA analysis to determine a transcriptome profile of cancer stemness in a mouse model.
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pubmed:affiliation |
Department of Histopathology and Morbid Anatomy, University of Dublin, Trinity College Dublin, Dublin 2, Ireland. cheffron@tcd.ie
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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