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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2007-6-26
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pubmed:abstractText |
Glutathione-S-transferase P1 (GSTP1) detoxifies a wide range of endogenous and exogenous carcinogens and anticancer agents such as cisplatin and doxorubicin. The aim of this study was to examine the association between GSTP1 polymorphism and both urothelial cancer susceptibility and adverse events of M-VAC (methotrexate, vinblastine, doxorubicin and cisplatin) chemotherapy in Japanese urothelial cancer patients.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0919-8172
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
14
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
500-4
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pubmed:meshHeading |
pubmed-meshheading:17593093-Aged,
pubmed-meshheading:17593093-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:17593093-Cisplatin,
pubmed-meshheading:17593093-Doxorubicin,
pubmed-meshheading:17593093-Female,
pubmed-meshheading:17593093-Gene Frequency,
pubmed-meshheading:17593093-Genetic Predisposition to Disease,
pubmed-meshheading:17593093-Genotype,
pubmed-meshheading:17593093-Glutathione S-Transferase pi,
pubmed-meshheading:17593093-Humans,
pubmed-meshheading:17593093-Leukopenia,
pubmed-meshheading:17593093-Male,
pubmed-meshheading:17593093-Metabolic Detoxication, Drug,
pubmed-meshheading:17593093-Methotrexate,
pubmed-meshheading:17593093-Middle Aged,
pubmed-meshheading:17593093-Polymorphism, Genetic,
pubmed-meshheading:17593093-Predictive Value of Tests,
pubmed-meshheading:17593093-Urologic Neoplasms,
pubmed-meshheading:17593093-Urothelium,
pubmed-meshheading:17593093-Vinblastine
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pubmed:year |
2007
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pubmed:articleTitle |
Association analysis of glutathione-S-transferase P1 (GSTP1) polymorphism with urothelial cancer susceptibility and myelosuppression after M-VAC chemotherapy.
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pubmed:affiliation |
Department of Urology, Kyushu University Graduate School of Medical Science, Fukuoka, Japan. yokoa@uro.med.kyushu-u.ac.jp
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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