| pubmed-article:17592941 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:17592941 | lifeskim:mentions | umls-concept:C0724441 | lld:lifeskim |
| pubmed-article:17592941 | lifeskim:mentions | umls-concept:C0035820 | lld:lifeskim |
| pubmed-article:17592941 | lifeskim:mentions | umls-concept:C0015726 | lld:lifeskim |
| pubmed-article:17592941 | lifeskim:mentions | umls-concept:C0009647 | lld:lifeskim |
| pubmed-article:17592941 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
| pubmed-article:17592941 | lifeskim:mentions | umls-concept:C0679079 | lld:lifeskim |
| pubmed-article:17592941 | lifeskim:mentions | umls-concept:C0449255 | lld:lifeskim |
| pubmed-article:17592941 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:17592941 | pubmed:dateCreated | 2007-6-26 | lld:pubmed |
| pubmed-article:17592941 | pubmed:abstractText | Six experiments with rat subjects examined the effect of yohimbine, an alpha-2 adrenergic autoreceptor antagonist, on the extinction of conditioned fear to a tone. Experiments 1 and 2 demonstrated that systemic administration of yohimbine (1.0 mg/kg) facilitated a long-term decrease in freezing after extinction, and this depended on pairing drug administration with extinction training. However, Experiments 3 and 4 demonstrated that yohimbine did not eradicate the original fear learning: Freezing was renewed when the tone was tested outside of the extinction context. Experiments 5 and 6 found that the contextually specific attenuation of fear produced by yohimbine transferred to another extinguished conditional stimulus (CS) and not to a nonextinguished CS. The results suggest that yohimbine, when administered in the presence of a neutral context, creates a form of inhibition in that context that allows that specific context to reduce fear of an extinguished CS. | lld:pubmed |
| pubmed-article:17592941 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17592941 | pubmed:language | eng | lld:pubmed |
| pubmed-article:17592941 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17592941 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:17592941 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17592941 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:17592941 | pubmed:month | Jun | lld:pubmed |
| pubmed-article:17592941 | pubmed:issn | 0735-7044 | lld:pubmed |
| pubmed-article:17592941 | pubmed:author | pubmed-author:MorrisRichard... | lld:pubmed |
| pubmed-article:17592941 | pubmed:author | pubmed-author:BoutonMark... | lld:pubmed |
| pubmed-article:17592941 | pubmed:copyrightInfo | Copyright (c) 2007 APA, all rights reserved. | lld:pubmed |
| pubmed-article:17592941 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:17592941 | pubmed:volume | 121 | lld:pubmed |
| pubmed-article:17592941 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:17592941 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:17592941 | pubmed:pagination | 501-14 | lld:pubmed |
| pubmed-article:17592941 | pubmed:dateRevised | 2007-12-3 | lld:pubmed |
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| pubmed-article:17592941 | pubmed:year | 2007 | lld:pubmed |
| pubmed-article:17592941 | pubmed:articleTitle | The effect of yohimbine on the extinction of conditioned fear: a role for context. | lld:pubmed |
| pubmed-article:17592941 | pubmed:affiliation | Department of Psychology, University of Vermont, Burlington, VT 05401, USA. | lld:pubmed |
| pubmed-article:17592941 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:17592941 | pubmed:publicationType | Research Support, N.I.H., Extramural | lld:pubmed |
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