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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
8
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pubmed:dateCreated |
2007-7-27
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pubmed:abstractText |
Diabetics have a significantly higher percentage of sperm with nuclear DNA (nDNA) fragmentation and increased levels of advanced glycation end products (AGEs), in their testis, epididymis and sperm. As the receptor for AGEs (RAGE) is important to oxidative stress and cell dysfunction, we hypothesise, that it may be involved in sperm nDNA damage.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0268-1161
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
22
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2169-77
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pubmed:meshHeading |
pubmed-meshheading:17588956-Adolescent,
pubmed-meshheading:17588956-Adult,
pubmed-meshheading:17588956-Diabetes Mellitus, Type 1,
pubmed-meshheading:17588956-Diabetes Mellitus, Type 2,
pubmed-meshheading:17588956-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:17588956-Epididymis,
pubmed-meshheading:17588956-Glycosylation End Products, Advanced,
pubmed-meshheading:17588956-Humans,
pubmed-meshheading:17588956-Male,
pubmed-meshheading:17588956-Middle Aged,
pubmed-meshheading:17588956-Receptors, Immunologic,
pubmed-meshheading:17588956-Semen,
pubmed-meshheading:17588956-Testis
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pubmed:year |
2007
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pubmed:articleTitle |
Distribution of the receptor for advanced glycation end products in the human male reproductive tract: prevalence in men with diabetes mellitus.
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pubmed:affiliation |
Department of Obstetrics and Gynaecology, Institute of Clinical Sciences, School of Medicine, Queen's University of Belfast, Grosvenor Road, Belfast, UK. c.mallidis@qub.ac.uk
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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