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pubmed-article:17587765pubmed:abstractTextThe ATP binding cassette transporters A1 and G1 (ABCA1/G1) and scavenger receptor class B type I (SR-BI) are key molecules in cholesterol efflux and atherogenesis. These genes are regulated by peroxisome proliferator-activated receptor gamma (PPARgamma) and liver X receptor (LXR). Telmisartan is an angiotensin type 1 receptor blocker which has been reported to act as a ligand for PPARgamma. We investigated whether PPARgamma-activating ARBs affect the expression of these genes and cholesterol efflux from macrophages.lld:pubmed
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pubmed-article:17587765pubmed:articleTitleTelmisartan enhances cholesterol efflux from THP-1 macrophages by activating PPARgamma.lld:pubmed
pubmed-article:17587765pubmed:affiliationDepartment of Internal Medicine, National Defense Medical College, Tokorozawa, Japan.lld:pubmed
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