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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2007-6-25
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pubmed:abstractText |
The ATP binding cassette transporters A1 and G1 (ABCA1/G1) and scavenger receptor class B type I (SR-BI) are key molecules in cholesterol efflux and atherogenesis. These genes are regulated by peroxisome proliferator-activated receptor gamma (PPARgamma) and liver X receptor (LXR). Telmisartan is an angiotensin type 1 receptor blocker which has been reported to act as a ligand for PPARgamma. We investigated whether PPARgamma-activating ARBs affect the expression of these genes and cholesterol efflux from macrophages.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/ATP-Binding Cassette Transporters,
http://linkedlifedata.com/resource/pubmed/chemical/Angiotensin-Converting Enzyme...,
http://linkedlifedata.com/resource/pubmed/chemical/Apolipoprotein A-I,
http://linkedlifedata.com/resource/pubmed/chemical/Benzimidazoles,
http://linkedlifedata.com/resource/pubmed/chemical/Benzoates,
http://linkedlifedata.com/resource/pubmed/chemical/Cholesterol,
http://linkedlifedata.com/resource/pubmed/chemical/DNA-Binding Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Lipoproteins, HDL,
http://linkedlifedata.com/resource/pubmed/chemical/Orphan Nuclear Receptors,
http://linkedlifedata.com/resource/pubmed/chemical/PPAR gamma,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Small Interfering,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Cytoplasmic and Nuclear,
http://linkedlifedata.com/resource/pubmed/chemical/Scavenger Receptors, Class B,
http://linkedlifedata.com/resource/pubmed/chemical/liver X receptor,
http://linkedlifedata.com/resource/pubmed/chemical/telmisartan
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1340-3478
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pubmed:author |
pubmed-author:AyaoriMakotoM,
pubmed-author:HisadaTetsuyaT,
pubmed-author:IwamotoNoriyukiN,
pubmed-author:KusuharaMasatoshiM,
pubmed-author:NakamuraHaruoH,
pubmed-author:NakayaKazuhiroK,
pubmed-author:OguraMasatsuneM,
pubmed-author:OhsuzuFumitakaF,
pubmed-author:SawadaShojiroS,
pubmed-author:TanakaNobukiyoN,
pubmed-author:YakushijiEmiE
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pubmed:issnType |
Print
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pubmed:volume |
14
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
133-41
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:17587765-ATP-Binding Cassette Transporters,
pubmed-meshheading:17587765-Angiotensin-Converting Enzyme Inhibitors,
pubmed-meshheading:17587765-Apolipoprotein A-I,
pubmed-meshheading:17587765-Benzimidazoles,
pubmed-meshheading:17587765-Benzoates,
pubmed-meshheading:17587765-Cells, Cultured,
pubmed-meshheading:17587765-Cholesterol,
pubmed-meshheading:17587765-DNA-Binding Proteins,
pubmed-meshheading:17587765-Gene Expression Regulation,
pubmed-meshheading:17587765-Humans,
pubmed-meshheading:17587765-Lipoproteins, HDL,
pubmed-meshheading:17587765-Macrophages,
pubmed-meshheading:17587765-Orphan Nuclear Receptors,
pubmed-meshheading:17587765-PPAR gamma,
pubmed-meshheading:17587765-RNA, Small Interfering,
pubmed-meshheading:17587765-Receptors, Cytoplasmic and Nuclear,
pubmed-meshheading:17587765-Scavenger Receptors, Class B
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pubmed:year |
2007
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pubmed:articleTitle |
Telmisartan enhances cholesterol efflux from THP-1 macrophages by activating PPARgamma.
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pubmed:affiliation |
Department of Internal Medicine, National Defense Medical College, Tokorozawa, Japan.
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pubmed:publicationType |
Journal Article
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