Linked Life Data

17587530

Source:http://linkedlifedata.com/resource/pubmed/id/17587530

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2007-10-9
pubmed:abstractText
The coupling of sequential injection analysis (SIA) and fluorimetric solid phase transduction is here applied to the determination of paracetamol in pharmaceuticals. The reaction product between the analyte and sodium nitrite in acidic medium is inserted, after alkalinization, in the system. This product is transitorily retained on the active solid sensing phase (the anionic solid support QAE A-25) developing its native fluorescence signal, which is measured at 325/430 nm for the excitation and emission wavelengths respectively. The described system is linear within the range 6.6-80 microg ml(-1), with a 2 microg ml(-1) detection limit and a 2.5% R.S.D (n=10). The proposed fluorimetric SIA optosensor has been applied to the determination of paracetamol in several pharmaceutical preparations, obtaining satisfactory results.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0731-7085
pubmed:author
pubmed:issnType
Print
pubmed:day
18
pubmed:volume
45
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
318-21
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
Fluorimetric SIA optosensing in pharmaceutical analysis: determination of paracetamol.
pubmed:affiliation
Department of Physical and Analytical Chemistry, Faculty of Experimental Sciences, University of Jaén, Paraje Las Lagunillas, E-32071 Jaén, Spain.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't