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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
7
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pubmed:dateCreated |
2007-7-11
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pubmed:abstractText |
We prepared silver particle dimers with single Cy5 molecules localized between coupled metal particles. The silver particles with a 20 nm diameter were chemically bound with single-stranded oligonucleotides. The dimers were formed by hybridization with double-length single-stranded oligonucleotides that contained single Cy5 molecules. The image analysis revealed that the single-molecule fluorescence was enhanced 7-fold on the metal monomer and 13-fold on the metal dimer relative to the free Cy5-labeled oligonucleotide in the absence of metal. The lifetimes were shortened on the silver monomers and further shortened on the silver dimers, demonstrating the near-field interaction mechanism of fluorophore with the metal substrate. Finite-difference time-domain (FDTD) calculations were employed to study the distribution of electric field near the metal monomer and dimer. The coupling effect of metal particle on the fluorescence enhancement was discussed.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/17580926-10639073,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17580926-11673890,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17580926-15080730,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17580926-15264814,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17580926-15453801,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17580926-15691498,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17580926-15826019,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17580926-15826096,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17580926-15826156,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17580926-16028889,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17580926-16028891,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17580926-16089488,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17580926-16144364,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17580926-16218733,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17580926-16351199,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17580926-16568977,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17580926-16683755,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17580926-16851886,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17580926-16852215,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17580926-16852350,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17580926-16853202,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17580926-16944907,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17580926-17092001,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17580926-19495214,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17580926-9751028
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1530-6984
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
7
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2101-7
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pubmed:dateRevised |
2011-5-17
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pubmed:meshHeading |
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pubmed:year |
2007
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pubmed:articleTitle |
Metal-enhanced single-molecule fluorescence on silver particle monomer and dimer: coupling effect between metal particles.
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pubmed:affiliation |
Center for Fluorescence Spectroscopy, University of Maryland School of Medicine, Department of Biochemistry and Molecular Biology, 725 West Lombard Street, Baltimore, Maryland 21201, USA.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, N.I.H., Extramural
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