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pubmed-article:17576865pubmed:abstractTextQT prolongation is an important risk factor for sudden cardiac death. About 35% of QT-interval variation is heritable. In a recent genome-wide association study, a common variant (rs10494366) in the nitric oxide synthase 1 adaptor protein (NOS1AP) gene was found to be associated with QT-interval variation. We tested for association of 2 NOS1AP variants with QT duration and sudden cardiac death.lld:pubmed
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pubmed-article:17576865pubmed:articleTitleCommon NOS1AP variants are associated with a prolonged QTc interval in the Rotterdam Study.lld:pubmed
pubmed-article:17576865pubmed:affiliationDepartment of Epidemiology and Biostatistics, Erasmus Medical Center, PO Box 2040, 3000 CA, Rotterdam, The Netherlands.lld:pubmed
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