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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6 Pt 2
|
pubmed:dateCreated |
1992-2-4
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pubmed:abstractText |
In a double-blind, parallel-group, multicenter comparative trial in 84 evaluable patients with severe, localized plaque psoriasis, 0.05% halobetasol propionate ointment proved significantly superior (p = 0.02) to 0.1% betamethasone valerate ointment with respect to the success rate, as indicated by ratings of "healed" or "marked improvement" (88.1% versus 64.3%). The therapeutic effect was observed within 5 days of the start of treatment in 76% and 67% of the patients treated with halobetasol propionate and betamethasone valerate ointments, respectively. Both preparations were well tolerated. Minor adverse effects at the site of application were reported in only 2% of the patients in each treatment group. Neither skin atrophy nor systemic adverse effects were observed.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Betamethasone 17-Valerate,
http://linkedlifedata.com/resource/pubmed/chemical/Clobetasol,
http://linkedlifedata.com/resource/pubmed/chemical/Ointments,
http://linkedlifedata.com/resource/pubmed/chemical/Vasoconstrictor Agents,
http://linkedlifedata.com/resource/pubmed/chemical/halobetasol
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0190-9622
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
25
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
1153-6
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1757607-Adult,
pubmed-meshheading:1757607-Aged,
pubmed-meshheading:1757607-Betamethasone 17-Valerate,
pubmed-meshheading:1757607-Chronic Disease,
pubmed-meshheading:1757607-Clobetasol,
pubmed-meshheading:1757607-Double-Blind Method,
pubmed-meshheading:1757607-Female,
pubmed-meshheading:1757607-Humans,
pubmed-meshheading:1757607-Male,
pubmed-meshheading:1757607-Middle Aged,
pubmed-meshheading:1757607-Ointments,
pubmed-meshheading:1757607-Patient Satisfaction,
pubmed-meshheading:1757607-Psoriasis,
pubmed-meshheading:1757607-Remission Induction,
pubmed-meshheading:1757607-Switzerland,
pubmed-meshheading:1757607-Vasoconstrictor Agents,
pubmed-meshheading:1757607-Wound Healing
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pubmed:year |
1991
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pubmed:articleTitle |
A comparative, multicenter, double blind trial of 0.05% halobetasol propionate ointment and 0.1% betamethasone valerate ointment in the treatment of patients with chronic, localized plaque psoriasis.
|
pubmed:affiliation |
Hôpital Cantonal, Fribourg, Switzerland.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Randomized Controlled Trial,
Controlled Clinical Trial,
Research Support, Non-U.S. Gov't,
Multicenter Study
|