Linked Life Data

17575448

Source:http://linkedlifedata.com/resource/pubmed/id/17575448

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2007-6-18
pubmed:abstractText
YtvA of Bacillus subtilis consists of light, oxygen or voltage (LOV) domain and sulfate transporter and anti-sigma antagonist (STAS) domain, and was reported to act as a photoreceptor, sensing light signals through the LOV domain, like a plant blue light receptor, phototropin. At the same time, YtvA was reported to act as a positive regulator for stress responsive-gene expression regulated by sigma(B) factor. Here we indicate that, like phototropins, the conserved Cys residue among the LOV domains is required for light-sensing in YtvA in vitro, possibly by the photoadduct formation, and YtvA forms a homodimer via its LOV domain, independently to light signal. We also indicate that, when ytvA expression is in normal level, light itself does not trigger sigma(B) activation, but a photo-enhancement of sigma(B) activity, activated by salt stress, occurs only in the presence of ytvA. The conserved Cys residue in the LOV domain and the STAS domain seem to be responsible for light-sensing and signal-transmission to the sigma(B) regulatory network, respectively.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0022-1260
pubmed:author
pubmed:issnType
Print
pubmed:volume
53
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
81-8
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
Enhancement of a sigma(B)-dependent stress response in Bacillus subtilis by light via YtvA photoreceptor.
pubmed:affiliation
Division of Integrative Environmental Sciences, Graduate School of Life and Environmental Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8572, Japan.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't