|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0006901,
umls-concept:C0017638,
umls-concept:C0019409,
umls-concept:C0027651,
umls-concept:C0031268,
umls-concept:C0032743,
umls-concept:C0232338,
umls-concept:C0441889,
umls-concept:C1326356,
umls-concept:C1428114,
umls-concept:C2603343
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|
pubmed:issue |
7
|
|
pubmed:dateCreated |
2007-7-3
|
|
pubmed:abstractText |
Many low-grade gliomas (World Health Organization grade II) respond to chemotherapy. Cerebral blood flow (CBF) and microvessel density may be critical for drug delivery. We used PET with (18)F-fluoro-ethyl-l-tyrosine (FET) to measure the spatial distribution of the amino acid carrier, which is located at the brain capillaries, and (15)O-H(2)O to measure tumor CBF.
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|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jul
|
|
pubmed:issn |
0161-5505
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
48
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
1047-52
|
|
pubmed:meshHeading |
pubmed-meshheading:17574979-Adult,
pubmed-meshheading:17574979-Amino Acid Transport Systems,
pubmed-meshheading:17574979-Brain Neoplasms,
pubmed-meshheading:17574979-Capillaries,
pubmed-meshheading:17574979-Cerebellum,
pubmed-meshheading:17574979-Female,
pubmed-meshheading:17574979-Fluorine Radioisotopes,
pubmed-meshheading:17574979-Glioma,
pubmed-meshheading:17574979-Humans,
pubmed-meshheading:17574979-Male,
pubmed-meshheading:17574979-Microcirculation,
pubmed-meshheading:17574979-Middle Aged,
pubmed-meshheading:17574979-Oxygen Isotopes,
pubmed-meshheading:17574979-Oxygen Radioisotopes,
pubmed-meshheading:17574979-Positron-Emission Tomography,
pubmed-meshheading:17574979-Radiopharmaceuticals,
pubmed-meshheading:17574979-Tyrosine,
pubmed-meshheading:17574979-Water
|
|
pubmed:year |
2007
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|
pubmed:articleTitle |
Spatial heterogeneity of low-grade gliomas at the capillary level: a PET study on tumor blood flow and amino acid uptake.
|
|
pubmed:affiliation |
PET Center, Division of Nuclear Medicine, University Hospital, Zürich, Switzerland.
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
