|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
2
|
|
pubmed:dateCreated |
2008-1-24
|
|
pubmed:abstractText |
NOD2/CARD15 is a susceptibility gene for Crohn's disease (CD). It is also involved, via different mutations, in the Blau syndrome. The syndrome of aseptic abscesses (AA) is characterized by visceral sterile collections of mature neutrophils that do not respond to antibiotics but regress quickly with corticosteroids. It is associated in two cases out of three with inflammatory bowel disease (IBD), and in particular with CD. We wanted to assess if changes on gene NOD2/CARD15 could contribute to the development of AA in patients with and without IBD.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
AIM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Feb
|
|
pubmed:issn |
0163-2116
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
53
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
490-9
|
|
pubmed:meshHeading |
pubmed-meshheading:17570063-Abdomen,
pubmed-meshheading:17570063-Abscess,
pubmed-meshheading:17570063-Adult,
pubmed-meshheading:17570063-Crohn Disease,
pubmed-meshheading:17570063-Female,
pubmed-meshheading:17570063-Gene Frequency,
pubmed-meshheading:17570063-Genetic Predisposition to Disease,
pubmed-meshheading:17570063-Humans,
pubmed-meshheading:17570063-Male,
pubmed-meshheading:17570063-Middle Aged,
pubmed-meshheading:17570063-Nod2 Signaling Adaptor Protein,
pubmed-meshheading:17570063-Polymorphism, Genetic,
pubmed-meshheading:17570063-Syndrome
|
|
pubmed:year |
2008
|
|
pubmed:articleTitle |
Analysis of the NOD2/CARD15 gene in patients affected with the aseptic abscesses syndrome with or without inflammatory bowel disease.
|
|
pubmed:affiliation |
Inserm, U384, Clermont-Ferrand, 63001, France. mandre@chu-clermontferrand.fr
|
|
pubmed:publicationType |
Journal Article
|
