Linked Life Data

17568595

Source:http://linkedlifedata.com/resource/pubmed/id/17568595

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-2
pubmed:dateCreated
2007-7-30
pubmed:abstractText
To study the influence of the particle size distribution (PSD), we measured the chromatographic performance of a series of sub-2 microm particle high performance liquid chromatography (HPLC) columns packed with four different particle mixtures having a purposely imposed different size distribution. Using the reduced kinetic plot representation by plotting the separation impedance (E(0)) versus the plate number ratio (N(opt)/N), the different columns could be classified according to their chromatographic performance without the need to specify a mean particle diameter or a molecular diffusion coefficient, as is needed in the classical reduced plate height and flow resistance analysis. The present analysis shows that it is not so much the width or span of the particle size distribution, but rather the presence of fines that greatly determines the chromatographic performance of particulate columns.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0021-9673
pubmed:author
pubmed:issnType
Print
pubmed:day
17
pubmed:volume
1161
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
224-33
pubmed:dateRevised
2009-1-15
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
Relation between the particle size distribution and the kinetic performance of packed columns. Application to a commercial sub-2 microm particle material.
pubmed:affiliation
Department of Chemical Engineering, Vrije Universiteit Brussel, Pleinlaan 2, 1050 Brussels, Belgium.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't