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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
8
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pubmed:dateCreated |
2007-8-16
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pubmed:abstractText |
Systemic inflammation causes vasodilation and impairs the vascular response to catecholamines. There is evidence that altered vasoreactivity is associated with increased production of free radicals. We studied the influence of systemic doses of the antioxidant N-acetylcysteine on inflammatory cytokines and renal plasma flow and on the systemic pressor response to norepinephrine during experimental endotoxemia.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0090-3493
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
35
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1869-75
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pubmed:meshHeading |
pubmed-meshheading:17568325-Acetylcysteine,
pubmed-meshheading:17568325-Adult,
pubmed-meshheading:17568325-Blood Circulation,
pubmed-meshheading:17568325-Cross-Over Studies,
pubmed-meshheading:17568325-Cytokines,
pubmed-meshheading:17568325-Dose-Response Relationship, Drug,
pubmed-meshheading:17568325-Double-Blind Method,
pubmed-meshheading:17568325-Free Radical Scavengers,
pubmed-meshheading:17568325-Humans,
pubmed-meshheading:17568325-Infusions, Intravenous,
pubmed-meshheading:17568325-Interleukin-1beta,
pubmed-meshheading:17568325-Lipopolysaccharides,
pubmed-meshheading:17568325-Male,
pubmed-meshheading:17568325-Oxidative Stress,
pubmed-meshheading:17568325-Renal Circulation,
pubmed-meshheading:17568325-Sepsis,
pubmed-meshheading:17568325-Tumor Necrosis Factor-alpha
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pubmed:year |
2007
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pubmed:articleTitle |
Effects of N-acetylcysteine against systemic and renal hemodynamic effects of endotoxin in healthy humans.
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pubmed:affiliation |
Department of Clinical Pharmacology, Medical University of Vienna, Austria.
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pubmed:publicationType |
Journal Article,
Randomized Controlled Trial
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