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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
4
|
| pubmed:dateCreated |
1992-2-5
|
| pubmed:abstractText |
A newly designed flow support catheter with a supporting wire mesh cage which can be expanded into a tubular configuration and then readily reduced was evaluated in mongrel dogs. Regional myocardial blood flow (RMBF) was measured using the radioactive microsphere technique in the area of both balloon-denuded instrumented and control non-instrumented coronary arteries following placement of either a fixed-wire or a higher profile rapid exchange flow support catheter. At 5, 20, and 180 min following delivery and expansion of either device, RMBF was not significantly different in left ventricular subepicardium and subendocardium perfused by the instrumented vs. the control coronary arteries. Angiography demonstrated widely patent instrumented arteries in 15/18 dogs; in no dog was side branch occlusion observed. Significant cage thrombus deposition was seen angiographically in 3 animals causing temporary total coronary occlusion in 1. Following reduction and removal of the flow support catheter, vessel patency was present in all dogs. The flow support catheter is an effective endovascular stenting device capable of providing structural arterial support, while simultaneously maintaining distal coronary blood flow. It is envisioned that the primary application of this catheter will be to enable primary salvage of vessels acutely injured during coronary angioplasty, by "tacking up" intimal flaps for an extended period. It may also provide a bridge to emergency surgical revascularization.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Dec
|
| pubmed:issn |
0098-6569
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
24
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
308-14
|
| pubmed:dateRevised |
2010-11-18
|
| pubmed:meshHeading |
pubmed-meshheading:1756571-Angioplasty, Balloon, Coronary,
pubmed-meshheading:1756571-Animals,
pubmed-meshheading:1756571-Coronary Angiography,
pubmed-meshheading:1756571-Coronary Circulation,
pubmed-meshheading:1756571-Coronary Vessels,
pubmed-meshheading:1756571-Dogs,
pubmed-meshheading:1756571-Female,
pubmed-meshheading:1756571-Heart Catheterization,
pubmed-meshheading:1756571-Hemodynamics,
pubmed-meshheading:1756571-Male,
pubmed-meshheading:1756571-Pilot Projects
|
| pubmed:year |
1991
|
| pubmed:articleTitle |
Flow support catheter for prolonged maintenance of coronary blood flow.
|
| pubmed:affiliation |
Heart Institute Hospital of the Good Samaritan, Los Angeles, California.
|
| pubmed:publicationType |
Journal Article
|