Linked Life Data

17564320

Source:http://linkedlifedata.com/resource/pubmed/id/17564320

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2007-6-13
pubmed:abstractText
The FasL-Fas system has been recognized as one of the apoptosis-inducing systems in the body. We studied the association between the serum levels of sFas, sFasL and TNF-alpha and the severity of the pathophysiological condition in 20 patients with multiple organ dysfunction syndrome (MODS) complicating generalized peritonitis. The serum levels of sFas and TNF-alpha were significantly higher in the patients who died than in those who survived. On the other hand, the sFasL level was significantly higher in the patients who survived than in those who died. A significant correlation was observed between the serum TNF-alpha level and the serum sFas level. These findings suggest that changes in the FasL-Fas system may be involved in the pathogenesis of MODS.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1078-0297
pubmed:author
pubmed:issnType
Print
pubmed:volume
115-116
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
235-42
pubmed:meshHeading
pubmed:year
2004
pubmed:articleTitle
Soluble Fas and soluble FasL in multiple organ dysfunction syndrome complicating diffuse peritonitis.
pubmed:affiliation
Department of Surgery, Iwate Prefectural Isawa Hospital, 61 Tatsugababa, Mizusawa 023-0864, Japan.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't