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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
2007-6-12
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pubmed:abstractText |
Variation in sensitivity to glucocorticoids observed in healthy population is influenced by genetic polymorphisms of the glucocorticoid receptor gene (NR3C1). N363S, ER22/23EK, and Bcl I have been previously described as glucocorticoid-sensitivity modulating polymorphisms. We investigated whether these variants may contribute to steroid-induced ocular hypertension and if they play a role as protective or risk factors during exogenous glucocorticoid administration.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/17563720-10088814,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17563720-10845579,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17563720-11133859,
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http://linkedlifedata.com/resource/pubmed/commentcorrection/17563720-9626107
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1090-0535
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
13
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
659-66
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pubmed:dateRevised |
2010-9-14
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pubmed:meshHeading |
pubmed-meshheading:17563720-Adult,
pubmed-meshheading:17563720-Corneal Surgery, Laser,
pubmed-meshheading:17563720-Female,
pubmed-meshheading:17563720-Fluorometholone,
pubmed-meshheading:17563720-Genetic Predisposition to Disease,
pubmed-meshheading:17563720-Genetic Variation,
pubmed-meshheading:17563720-Glucocorticoids,
pubmed-meshheading:17563720-Heterozygote,
pubmed-meshheading:17563720-Humans,
pubmed-meshheading:17563720-Hungary,
pubmed-meshheading:17563720-Intraocular Pressure,
pubmed-meshheading:17563720-Male,
pubmed-meshheading:17563720-Middle Aged,
pubmed-meshheading:17563720-Ocular Hypertension,
pubmed-meshheading:17563720-Postoperative Care,
pubmed-meshheading:17563720-Prednisolone,
pubmed-meshheading:17563720-Receptors, Glucocorticoid,
pubmed-meshheading:17563720-Retreatment,
pubmed-meshheading:17563720-Steroids
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pubmed:year |
2007
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pubmed:articleTitle |
The variant N363S of glucocorticoid receptor in steroid-induced ocular hypertension in Hungarian patients treated with photorefractive keratectomy.
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pubmed:affiliation |
Department of Ophthalmology, KFKI Research Institute for Particle and Nuclear Physics of the Hungarian Academy of Sciences, Budapest, Hungary. szabo_viktoria@hotmail.com
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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