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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
25
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pubmed:dateCreated |
2007-6-26
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pubmed:abstractText |
In the main analysis of the Canadian Continuous Positive Airway Pressure (CPAP) for Patients with Central Sleep Apnea (CSA) and Heart Failure Trial (CANPAP), CPAP had no effect on heart transplant-free survival; however, CPAP only reduced the mean apnea-hypopnea index to 19 events per hour of sleep, which remained above the trial inclusion threshold of 15. This stratified analysis of CANPAP tested the hypothesis that suppression of CSA below this threshold by CPAP would improve left ventricular ejection fraction and heart transplant-free survival.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1524-4539
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pubmed:author |
pubmed-author:ArztMichaelM,
pubmed-author:BelenkieIsraelI,
pubmed-author:BradleyT DouglasTD,
pubmed-author:CANPAP Investigators,
pubmed-author:FergusonKathleenK,
pubmed-author:FleethamJohnJ,
pubmed-author:FlorasJohn SJS,
pubmed-author:HanlyPatrickP,
pubmed-author:KimoffR JohnRJ,
pubmed-author:LoganAlexander GAG,
pubmed-author:MorrisonDebraD,
pubmed-author:PfeiferMichaelM,
pubmed-author:RyanClodaghC,
pubmed-author:SeriesFredericF,
pubmed-author:SmilovitchMarkM,
pubmed-author:TomlinsonGeorgeG
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pubmed:issnType |
Electronic
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pubmed:day |
26
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pubmed:volume |
115
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
3173-80
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:17562959-Aged,
pubmed-meshheading:17562959-Cardiovascular Agents,
pubmed-meshheading:17562959-Cheyne-Stokes Respiration,
pubmed-meshheading:17562959-Combined Modality Therapy,
pubmed-meshheading:17562959-Continuous Positive Airway Pressure,
pubmed-meshheading:17562959-Exercise Tolerance,
pubmed-meshheading:17562959-Female,
pubmed-meshheading:17562959-Heart Failure,
pubmed-meshheading:17562959-Heart Transplantation,
pubmed-meshheading:17562959-Humans,
pubmed-meshheading:17562959-Kaplan-Meier Estimate,
pubmed-meshheading:17562959-Male,
pubmed-meshheading:17562959-Middle Aged,
pubmed-meshheading:17562959-Oxygen,
pubmed-meshheading:17562959-Partial Pressure,
pubmed-meshheading:17562959-Polysomnography,
pubmed-meshheading:17562959-Proportional Hazards Models,
pubmed-meshheading:17562959-Severity of Illness Index,
pubmed-meshheading:17562959-Single-Blind Method,
pubmed-meshheading:17562959-Sleep Apnea, Central,
pubmed-meshheading:17562959-Stroke Volume,
pubmed-meshheading:17562959-Survival Analysis,
pubmed-meshheading:17562959-Sympathetic Nervous System,
pubmed-meshheading:17562959-Treatment Outcome
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pubmed:year |
2007
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pubmed:articleTitle |
Suppression of central sleep apnea by continuous positive airway pressure and transplant-free survival in heart failure: a post hoc analysis of the Canadian Continuous Positive Airway Pressure for Patients with Central Sleep Apnea and Heart Failure Trial (CANPAP).
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pubmed:affiliation |
University of Toronto, Toronto, Ontario, Canada.
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pubmed:publicationType |
Journal Article,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't,
Multicenter Study
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