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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
|
pubmed:dateCreated |
1992-2-6
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pubmed:abstractText |
The evaluability and reliability of proliferative activity (expressed as 3H-thymidine labeling index, 3H-TdR LI) and ploidy determinations on core needle biopsies were compared with those obtained on surgical material from the same breast cancers. The evaluability of 3H-TdR LI on core needle biopsies was markedly lower than that on surgical material (53% vs 100%), and the association between 3H-TdR LI values in the 16 cases with both evaluable determinations was poor (rs = 0.45). Conversely, determinations of ploidy on core needle biopsy and surgical material provided superimposable results, in terms of evaluability (91% vs 100%) and reliability (rs = 0.99). Further efforts are needed to improve sampling procedures for a reliable assessment of biological markers.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Sep
|
pubmed:issn |
0167-6806
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
19
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
33-7
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1756265-Biopsy,
pubmed-meshheading:1756265-Biopsy, Needle,
pubmed-meshheading:1756265-Breast Neoplasms,
pubmed-meshheading:1756265-Cell Division,
pubmed-meshheading:1756265-DNA, Neoplasm,
pubmed-meshheading:1756265-Female,
pubmed-meshheading:1756265-Humans,
pubmed-meshheading:1756265-Kinetics,
pubmed-meshheading:1756265-Ploidies,
pubmed-meshheading:1756265-Reproducibility of Results,
pubmed-meshheading:1756265-Thymidine
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pubmed:year |
1991
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pubmed:articleTitle |
Comparing core needle to surgical biopsies in breast cancer for cell kinetic and ploidy studies.
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pubmed:affiliation |
Division of Oncologia Sperimentale C, Istituto Nazionale Tumori, Milan, Italy.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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