|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0004057,
umls-concept:C0004083,
umls-concept:C0032529,
umls-concept:C0032659,
umls-concept:C0152035,
umls-concept:C0245726,
umls-concept:C0332161,
umls-concept:C0376249,
umls-concept:C0871261,
umls-concept:C1335271,
umls-concept:C1418217,
umls-concept:C1704632,
umls-concept:C1706817,
umls-concept:C2911692
|
|
pubmed:issue |
6
|
|
pubmed:dateCreated |
2007-6-11
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|
pubmed:abstractText |
Aspirin is a frequently prescribed drug for primary and secondary prevention of myocardial infarction, stroke and cardiovascular death. However, aspirin resistance may affect up to 45% of the population. Little is known on the role of genetic factors that contribute to resistance or augmented response to aspirin in different human populations.
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|
pubmed:language |
eng
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pubmed:journal |
|
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pubmed:citationSubset |
IM
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|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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|
pubmed:month |
Jun
|
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pubmed:issn |
1744-8042
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pubmed:author |
pubmed-author:ChenBi-LianBL,
pubmed-author:JeuJ FJF,
pubmed-author:LeeL FLF,
pubmed-author:LeiHei-PingHP,
pubmed-author:MaoYan-MeiYM,
pubmed-author:OzdemirVuralV,
pubmed-author:StamJ WJW,
pubmed-author:WangLian-CiLC,
pubmed-author:YaeYY,
pubmed-author:ZhangWeiW,
pubmed-author:ZhouHong-HaoHH
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|
pubmed:issnType |
Electronic
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|
pubmed:volume |
8
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
577-86
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|
pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:17559347-Adult,
pubmed-meshheading:17559347-Aspirin,
pubmed-meshheading:17559347-Cyclooxygenase 1,
pubmed-meshheading:17559347-Dose-Response Relationship, Drug,
pubmed-meshheading:17559347-Female,
pubmed-meshheading:17559347-Gene Frequency,
pubmed-meshheading:17559347-Humans,
pubmed-meshheading:17559347-Integrin beta3,
pubmed-meshheading:17559347-Male,
pubmed-meshheading:17559347-Platelet Aggregation,
pubmed-meshheading:17559347-Polymorphism, Genetic,
pubmed-meshheading:17559347-Prospective Studies,
pubmed-meshheading:17559347-Receptors, Purinergic P2,
pubmed-meshheading:17559347-Receptors, Purinergic P2Y1
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pubmed:year |
2007
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|
pubmed:articleTitle |
Frequency of genetic polymorphisms of COX1, GPIIIa and P2Y1 in a Chinese population and association with attenuated response to aspirin.
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|
pubmed:affiliation |
Central South University, Institute of Clinical Pharmacology, Pharmacogenetics Research Institute, Changsha, Hunan 410078, China.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Research Support, Non-U.S. Gov't
|
