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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1992-1-24
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pubmed:abstractText |
Bone mineral density (BMD) was measured in 133 female subjects (age: 61.7 +/- 16.3 years) by dual energy X-ray absorptiometry (DEXA). Vertebral bone mineral density (BMD; L1-L4) and BMD of the whole upper femoral extremity were taken into account. In addition, skinfold thickness was measured with a callipers on the dorsum of the nondominant hand. A significant negative correlation was found between skinfold thickness and age (r = -0.623, p less than 0.0001). Both vertebral and femoral BMD decreased with age and the slopes were similar to those observed by other authors. Skinfold thickness was significantly correlated with vertebral (r = 0.364, p less than 0.0001) and femoral BMD (r = 0.486, p less than 0.0001). Skin and bone are connective tissues whose extracellular matrix mainly contains type I collagen. It is postulated that age-related skin atrophy and bone atrophy have a common genetic mechanism. Skinfold thickness measurement may help in defining the women at risk for osteoporotic bone fractures who should be referred for a DEXA examination.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:issn |
0001-5180
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
141
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
239-44
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pubmed:dateRevised |
2007-7-2
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pubmed:meshHeading |
pubmed-meshheading:1755285-Absorptiometry, Photon,
pubmed-meshheading:1755285-Adolescent,
pubmed-meshheading:1755285-Adult,
pubmed-meshheading:1755285-Aged,
pubmed-meshheading:1755285-Aging,
pubmed-meshheading:1755285-Atrophy,
pubmed-meshheading:1755285-Bone Density,
pubmed-meshheading:1755285-Female,
pubmed-meshheading:1755285-Femur,
pubmed-meshheading:1755285-Humans,
pubmed-meshheading:1755285-Lumbar Vertebrae,
pubmed-meshheading:1755285-Middle Aged,
pubmed-meshheading:1755285-Osteoporosis,
pubmed-meshheading:1755285-Skin,
pubmed-meshheading:1755285-Skinfold Thickness
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pubmed:year |
1991
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pubmed:articleTitle |
Relationships between bone and skin atrophies during aging.
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pubmed:affiliation |
Laboratoire de Biologie du Tissu Osseux, Faculté de Médecine, Saint-Etienne, France.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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