Linked Life Data

17552495

Source:http://linkedlifedata.com/resource/pubmed/id/17552495

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
14
pubmed:dateCreated
2007-7-13
pubmed:abstractText
A suspension array for multiplexed immunoassays has been developed using shape-coded silica nanotubes (SNTs) as coding materials. Fabricated by multistep anodization template synthesis, each shape-coded SNT has several segments with different reflectance values depending on their diameters and wall thicknesses. Therefore, the code of each SNT can be "read-out" under a conventional optical microscope. The suspension array with shape-coded SNTs has shown high stability and dispersibility in aqueous buffer media and high detection sensitivity. The SNTs have not shown any visible degradation while submerged in aqueous solution for 7 months, the tubular structure and silanol groups on the inner and outer surfaces allow SNTs to disperse evenly in buffer solution, and the detection limit of an IgG protein is about 6 pM with 1.5 x 10(6) SNTs per mL. We have demonstrated the high selectivity of the SNTs suspension array for the detection of multianalytes in the multiplexed immunoassay experiments.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0003-2700
pubmed:author
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
79
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
5257-63
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
Suspension array with shape-coded silica nanotubes for multiplexed immunoassays.
pubmed:affiliation
Department of Chemistry and Biochemistry, University of Maryland, College Park, Maryland 20742, USA.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't, Research Support, N.I.H., Extramural