Linked Life Data

1755065

Source:http://linkedlifedata.com/resource/pubmed/id/1755065

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1992-1-30
pubmed:abstractText
Partially purified Fasciola gigantica worm antigens were evaluated in an enzyme-linked immunosorbent assay (ELISA) for the specific serological diagnosis of fascioliasis. The diagnostic potential of 10 antigen fractions derived from gel-filtration peaks (II & III) were evaluated individually or in combination against a panel of admission sera obtained from 50 patients subsequently diagnosed as having a variety of systemic parasitic diseases, and from 10 healthy volunteers with no recent history of parasitic infections. Fractions 2 and 10 were highly specific for Fasciola infection and failed to react with sera from any patient with other parasitic diseases or from controls. All other fractions exhibited reactivity with the majority of sera from the fascioliasis patients, but also with some sera from patients infected with other parasites. Based on these results, the ELISA, as outlined here, should be considered as a rapid and specific technique for the diagnosis of fascioliasis and also as an epidemiological surveillance technique in areas endemic for F. gigantica infection.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0035-9203
pubmed:author
pubmed:issnType
Print
pubmed:volume
85
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
535-7
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:articleTitle
A purified Fasciola gigantica worm antigen for the serodiagnosis of human fascioliasis.
pubmed:affiliation
Basic Science Division, US Naval Medical Research Unit No. 3, Cairo, Egypt.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, Non-P.H.S.