Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2007-6-4
pubmed:abstractText
The incidence of non-alcoholic steatohepatitis, a disorder linked to visceral adiposity, insulin resistance, dyslipidemia, and type 2 diabetes mellitus, is increasing with the rise in the prevalence of the metabolic syndrome. This review focuses on animal models of steatohepatitis currently used to study (1) the mechanisms regulating hepatic lipid, glucose, and cholesterol homeostasis and (2) inflammatory recruitment and fibrogenesis in the steatotic liver. The ultimate aim of this research is to gain insights into the role of hepatic lipid, inflammation, and fibrosis in human non-alcoholic fatty liver disease.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
1089-3261
pubmed:author
pubmed:issnType
Print
pubmed:volume
11
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
55-74, viii
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
Pathogenesis of NASH: animal models.
pubmed:affiliation
Westmead Millennium Institute, Storr Liver Unit, Westmead, NSW 2145, Australia. roslyn_london@wmi.usyd.edu.au
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't