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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2007-6-4
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pubmed:abstractText |
In vitro models for joint diseases often focus on a single cell type, such as chondrocytes in osteoarthritis (OA) or fibroblast-like synoviocytes (synoviocytes) in rheumatoid arthritis (RA). However, these joint diseases affect the whole joint and interaction between chondrocytes and synoviocytes may play an important role in disease pathology. The current study was designed to study the use of the alginate recovered chondrocyte method as a model for cartilage degradation and to study interaction between chondrocytes and synoviocytes.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
0392-856X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
25
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
239-45
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pubmed:meshHeading |
pubmed-meshheading:17543148-Alginates,
pubmed-meshheading:17543148-Animals,
pubmed-meshheading:17543148-Arthritis, Rheumatoid,
pubmed-meshheading:17543148-Cartilage,
pubmed-meshheading:17543148-Cattle,
pubmed-meshheading:17543148-Cell Communication,
pubmed-meshheading:17543148-Cells, Cultured,
pubmed-meshheading:17543148-Chondrocytes,
pubmed-meshheading:17543148-Collagen,
pubmed-meshheading:17543148-Disease Models, Animal,
pubmed-meshheading:17543148-Fibroblasts,
pubmed-meshheading:17543148-Glucuronic Acid,
pubmed-meshheading:17543148-Hexuronic Acids,
pubmed-meshheading:17543148-Interleukin-1beta,
pubmed-meshheading:17543148-Osteoarthritis,
pubmed-meshheading:17543148-Proteoglycans,
pubmed-meshheading:17543148-Synovial Membrane,
pubmed-meshheading:17543148-Tumor Necrosis Factor-alpha
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pubmed:articleTitle |
Fibroblast-like synoviocyte-chondrocyte interaction in cartilage degradation.
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pubmed:affiliation |
Bio Sciences, TNO Quality of Life, Leiden, The Netherland.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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