|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0004927,
umls-concept:C0007137,
umls-concept:C0012899,
umls-concept:C0127400,
umls-concept:C0205460,
umls-concept:C0208973,
umls-concept:C0558353,
umls-concept:C1156235,
umls-concept:C1517892,
umls-concept:C1704666,
umls-concept:C2717841
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|
pubmed:issue |
7
|
|
pubmed:dateCreated |
2007-6-4
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|
pubmed:abstractText |
Squamous cell carcinoma (SCC) of the tongue shows aggressive behaviour and a poor prognosis. Clinicopathological parameters fail to provide reliable prognostic information, so the search continues for new molecular markers for this tumour. Chromatin assembly factor-1 (CAF-1) plays a major role in chromatin assembly during cell replication and DNA repair and has been proposed as a new proliferation marker. The aim of this study was to investigate its expression in SCC of the tongue.
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pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
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|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jun
|
|
pubmed:issn |
0309-0167
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|
pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
50
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
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pubmed:pagination |
911-9
|
|
pubmed:meshHeading |
pubmed-meshheading:17543081-Aged,
pubmed-meshheading:17543081-Aged, 80 and over,
pubmed-meshheading:17543081-Blotting, Western,
pubmed-meshheading:17543081-Carcinoma, Squamous Cell,
pubmed-meshheading:17543081-Cell Proliferation,
pubmed-meshheading:17543081-DNA, Neoplasm,
pubmed-meshheading:17543081-DNA Repair,
pubmed-meshheading:17543081-Down-Regulation,
pubmed-meshheading:17543081-Female,
pubmed-meshheading:17543081-Fluorescent Antibody Technique, Direct,
pubmed-meshheading:17543081-Humans,
pubmed-meshheading:17543081-Immunoenzyme Techniques,
pubmed-meshheading:17543081-Male,
pubmed-meshheading:17543081-Middle Aged,
pubmed-meshheading:17543081-Proliferating Cell Nuclear Antigen,
pubmed-meshheading:17543081-Survival Rate,
pubmed-meshheading:17543081-Tongue Neoplasms,
pubmed-meshheading:17543081-Transcription Factors,
pubmed-meshheading:17543081-Tumor Markers, Biological
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|
pubmed:year |
2007
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|
pubmed:articleTitle |
Chromatin assembly factor-1 (CAF-1)-mediated regulation of cell proliferation and DNA repair: a link with the biological behaviour of squamous cell carcinoma of the tongue?
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|
pubmed:affiliation |
Department of Biomorphological and Functional Sciences, Federico II University, Pathology Section, Faculty of Medicine and Surgery, Naples, Italy. staibano@unina.it
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pubmed:publicationType |
Journal Article
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