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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2007-6-1
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pubmed:abstractText |
The control of tuberculosis (TB) requires methods for rapid detection and tracing sources of infection, so that further transmission can be arrested. Recent developments in molecular biology have resulted in techniques that allow prompt identification and tracking specific strains of M. tuberculosis as they spread through the population. Most of these techniques take advantage of M. tuberculosis DNA polymorphism and are based on various repetitive DNA elements as genetic markers. Each method yields strain-specific genetic profiles (fingerprints). Strains showing identical fingerprints are referred to as clustered and are usually associated with recent transmission, whereas strains whose fingerprints are unique are presumed to represent remote transmission, a reactivation of infection acquired in the distant past.
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pubmed:language |
pol
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
0867-7077
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
75
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
22-31
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:17541909-Adult,
pubmed-meshheading:17541909-Aged,
pubmed-meshheading:17541909-Aged, 80 and over,
pubmed-meshheading:17541909-Antitubercular Agents,
pubmed-meshheading:17541909-Bacterial Typing Techniques,
pubmed-meshheading:17541909-Cluster Analysis,
pubmed-meshheading:17541909-Contact Tracing,
pubmed-meshheading:17541909-DNA Fingerprinting,
pubmed-meshheading:17541909-Databases, Factual,
pubmed-meshheading:17541909-Female,
pubmed-meshheading:17541909-Genetic Markers,
pubmed-meshheading:17541909-Humans,
pubmed-meshheading:17541909-Interspersed Repetitive Sequences,
pubmed-meshheading:17541909-Isoniazid,
pubmed-meshheading:17541909-Male,
pubmed-meshheading:17541909-Middle Aged,
pubmed-meshheading:17541909-Molecular Epidemiology,
pubmed-meshheading:17541909-Mycobacterium tuberculosis,
pubmed-meshheading:17541909-Poland,
pubmed-meshheading:17541909-Polymerase Chain Reaction,
pubmed-meshheading:17541909-Polymorphism, Restriction Fragment Length,
pubmed-meshheading:17541909-Sensitivity and Specificity,
pubmed-meshheading:17541909-Tuberculosis, Multidrug-Resistant,
pubmed-meshheading:17541909-Tuberculosis, Pulmonary
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pubmed:year |
2007
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pubmed:articleTitle |
[The significance of spoligotyping method in epidemiological investigations of tuberculosis].
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pubmed:affiliation |
Zak?ad Mikrobiologii Instytutu Gru?licy i Chorób P?uc w Warszawie. e.kopec@igichp.edu.pl
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pubmed:publicationType |
Journal Article,
English Abstract,
Evaluation Studies
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