Source:http://linkedlifedata.com/resource/pubmed/id/17541276
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
2007-8-6
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pubmed:abstractText |
Recent evidence suggests that both neutrophilic and eosinophilic inflammation persist in the airways of patients with severe asthma. Neutrophils can secrete a variety of mediators which may augment the migration of eosinophils. We have reported that activated neutrophils augment the trans-basement membrane migration (TBM) of eosinophils in vitro. Theophylline has been shown to modulate some functions of both neutrophils and eosinophils. The objective of this study was to evaluate whether theophylline modulates the neutrophil-dependent augmentation of eosinophil TBM.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
1423-0097
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
143 Suppl 1
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
44-9
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pubmed:meshHeading |
pubmed-meshheading:17541276-Adult,
pubmed-meshheading:17541276-Basement Membrane,
pubmed-meshheading:17541276-Cells, Cultured,
pubmed-meshheading:17541276-Chemotaxis, Leukocyte,
pubmed-meshheading:17541276-Drug Evaluation, Preclinical,
pubmed-meshheading:17541276-Eosinophils,
pubmed-meshheading:17541276-Female,
pubmed-meshheading:17541276-Humans,
pubmed-meshheading:17541276-Interleukin-8,
pubmed-meshheading:17541276-Leukotriene B4,
pubmed-meshheading:17541276-Male,
pubmed-meshheading:17541276-Neutrophils,
pubmed-meshheading:17541276-Respiratory Burst,
pubmed-meshheading:17541276-Superoxides,
pubmed-meshheading:17541276-Theophylline
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pubmed:year |
2007
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pubmed:articleTitle |
Theophylline attenuates the neutrophil-dependent augmentation of eosinophil trans-basement membrane migration.
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pubmed:affiliation |
Department of Respiratory Medicine, Saitama Medical University, Saitama, Japan.
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pubmed:publicationType |
Journal Article,
In Vitro
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