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rdf:type |
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|
lifeskim:mentions |
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pubmed:issue |
7
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pubmed:dateCreated |
2007-5-31
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pubmed:abstractText |
Small-animal PET is acquiring importance for pre-clinical studies. In rodents, radiotracers are usually administrated via the tail vein. This procedure can be very difficult and time-consuming as soft tissue extravasations are very frequent and tail scars can prevent repeated injections after initial failure. The aim of our study was to compare the retro-orbital (RO) versus tail vein intravenous (i.v.) administration of (18)F-FDG and (11)C-choline in mice for small-animal PET studies.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0143-3636
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
28
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
547-53
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pubmed:meshHeading |
pubmed-meshheading:17538396-Animals,
pubmed-meshheading:17538396-Carbon Radioisotopes,
pubmed-meshheading:17538396-Choline,
pubmed-meshheading:17538396-Female,
pubmed-meshheading:17538396-Fluorodeoxyglucose F18,
pubmed-meshheading:17538396-Image Enhancement,
pubmed-meshheading:17538396-Injections, Intravenous,
pubmed-meshheading:17538396-Metabolic Clearance Rate,
pubmed-meshheading:17538396-Mice,
pubmed-meshheading:17538396-Mice, Inbred ICR,
pubmed-meshheading:17538396-Organ Specificity,
pubmed-meshheading:17538396-Positron-Emission Tomography,
pubmed-meshheading:17538396-Radiopharmaceuticals,
pubmed-meshheading:17538396-Reproducibility of Results,
pubmed-meshheading:17538396-Sensitivity and Specificity,
pubmed-meshheading:17538396-Tissue Distribution,
pubmed-meshheading:17538396-Whole Body Imaging
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pubmed:year |
2007
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pubmed:articleTitle |
Retro-orbital injection is an effective route for radiopharmaceutical administration in mice during small-animal PET studies.
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pubmed:affiliation |
Nuclear Medicine Department, Azienda Ospedaliero-Universitaria di Bologna Policlinico S. Orsola-Malpighi, Italy.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Evaluation Studies
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