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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2007-6-29
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pubmed:abstractText |
The RUNX1 (also known as AML1) gene is observed frequently as the target of chromosomal rearrangements in human acute leukemia. We describe here a previously unreported rearrangement, t(11;21)(q13;q22), that disrupts the RUNX1 gene in a patient with acute leukemia and the molecular analysis of the fusion gene.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0902-4441
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
79
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
25-31
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pubmed:meshHeading |
pubmed-meshheading:17532767-Base Sequence,
pubmed-meshheading:17532767-Cell Line, Tumor,
pubmed-meshheading:17532767-Chromosomes, Human, Pair 11,
pubmed-meshheading:17532767-Chromosomes, Human, Pair 21,
pubmed-meshheading:17532767-Core Binding Factor Alpha 2 Subunit,
pubmed-meshheading:17532767-DNA Primers,
pubmed-meshheading:17532767-Female,
pubmed-meshheading:17532767-Humans,
pubmed-meshheading:17532767-Karyotyping,
pubmed-meshheading:17532767-Leukemia, Monocytic, Acute,
pubmed-meshheading:17532767-Middle Aged,
pubmed-meshheading:17532767-Neoplasm Proteins,
pubmed-meshheading:17532767-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:17532767-Translocation, Genetic
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pubmed:year |
2007
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pubmed:articleTitle |
LRP16 is fused to RUNX1 in monocytic leukemia cell line with t(11;21)(q13;q22).
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pubmed:affiliation |
Department of Hematology and Oncology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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