Source:http://linkedlifedata.com/resource/pubmed/id/17532575
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
7
|
| pubmed:dateCreated |
2007-9-14
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| pubmed:abstractText |
The goal of the study was to analyse plasma procalcitonin (PCT) concentrations during infectious events of burns in ICU. Clinical and laboratory data were collected at admission and twice a week in burned patients admitted with a total body surface area (TBSA) >20%. Procalcitonin was determined using both a semi-quantitative detection (PCT-Q) and a quantitative immunoluminometric method (PCT-Lumi). A total of 359 time points in 25 consecutive patients with 40+/-17% (20-86%) TBSA burned, defined as a procalcitonin concentration associated with an inflammatory status according to society critical care medicine definition, were made. The principal site of infection was the respiratory tract (84% of patients required mechanical ventilation). PCT-Lumi values corresponded to the four semi-quantitative ranges of PCT-Q and statistically reflected the simultaneously observed inflammatory status (Kruskall-Wallis test). The area under the receiver operating characteristic curve for C-reactive protein (CRP) was higher than those for PCT and white blood cell (WBC) count, but this difference was not significant. The optimum PCT cut-off value was 0.534 ng/ml with sensitivity and specificity of 42.4% and 88.8%, respectively. However, PCT does not appear to be superior to C-reactive protein (CRP) and white blood count (WBC) as diagnosis marker of sepsis in burns. PCT is not sufficient to diagnose and to follow infection in burns admitted in ICU.
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| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Biological Markers,
http://linkedlifedata.com/resource/pubmed/chemical/C-Reactive Protein,
http://linkedlifedata.com/resource/pubmed/chemical/Calcitonin,
http://linkedlifedata.com/resource/pubmed/chemical/Protein Precursors,
http://linkedlifedata.com/resource/pubmed/chemical/procalcitonin
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| pubmed:status |
MEDLINE
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| pubmed:month |
Nov
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| pubmed:issn |
0305-4179
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| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
33
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| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
860-4
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| pubmed:dateRevised |
2011-11-17
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| pubmed:meshHeading |
pubmed-meshheading:17532575-Adolescent,
pubmed-meshheading:17532575-Adult,
pubmed-meshheading:17532575-Aged,
pubmed-meshheading:17532575-Aged, 80 and over,
pubmed-meshheading:17532575-Biological Markers,
pubmed-meshheading:17532575-Burns,
pubmed-meshheading:17532575-C-Reactive Protein,
pubmed-meshheading:17532575-Calcitonin,
pubmed-meshheading:17532575-Cross Infection,
pubmed-meshheading:17532575-Female,
pubmed-meshheading:17532575-Humans,
pubmed-meshheading:17532575-Intensive Care,
pubmed-meshheading:17532575-Leukocyte Count,
pubmed-meshheading:17532575-Luminescent Measurements,
pubmed-meshheading:17532575-Male,
pubmed-meshheading:17532575-Middle Aged,
pubmed-meshheading:17532575-Prospective Studies,
pubmed-meshheading:17532575-Protein Precursors,
pubmed-meshheading:17532575-Sepsis
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| pubmed:year |
2007
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| pubmed:articleTitle |
Evaluation of serum procalcitonin concentration in the ICU following severe burn.
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| pubmed:affiliation |
Hôpital d'Instruction des Armées Percy, Centre de Traitement des Brûlés, 101 avenue Henri Barbusse, 92141 Clamart, France. BAGOL@AOL.com
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| pubmed:publicationType |
Journal Article
|