Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
11
pubmed:dateCreated
2007-5-28
pubmed:abstractText
Symptomatic mitral stenosis (MS) develops in 7% to 21% of patients after percutaneous mitral balloon valvotomy (PMV). Treatment options for these patients are surgical mitral valve replacement (MVR) or repeated PMV. However, no comparisons were made between these 2 procedures regarding long-term outcome. This retrospective study compares the long-term outcome of 888 patients with symptomatic MS after MVR or repeated PMV who underwent PMV from April 1988 to December 2003. Thirty-two patients subsequently underwent repeated PMV, and 59 patients underwent MVR for symptomatic MS. Mean follow-up was 85 +/- 43 months with a maximum follow-up of 15 years. Patients with MVR have more unfavorable clinical characteristics, including a higher incidence of atrial fibrillation and severe mitral regurgitation. Event-free survival was similar between the 2 groups up to 40 months after the procedure; 3-year event-free survival rates were 96.6% for MVR patients and 90.0% for repeated PMV patients (p = 0.215). However, after 40 months, the outcome was more favorable for MVR. Comparing MVR versus PMV, 6-year event-free survival rates were 93.0% versus 75.9% (p = 0.036), and 9-year event-free survival rates were 90.4% versus 36.0% (p <0.001). In conclusion, the long-term outcome of patients with symptomatic MS after previous PMV was more favorable after MVR than after repeated PMV. These data suggest that MVR may be the preferred mode of therapy in patients with unfavorable valve morphologic characteristics and no co-morbid disease.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0002-9149
pubmed:author
pubmed:issnType
Print
pubmed:day
1
pubmed:volume
99
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1571-4
pubmed:dateRevised
2010-11-18
pubmed:meshHeading
pubmed-meshheading:17531583-Adult, pubmed-meshheading:17531583-Atrial Fibrillation, pubmed-meshheading:17531583-Balloon Dilation, pubmed-meshheading:17531583-Disease-Free Survival, pubmed-meshheading:17531583-Echocardiography, Doppler, Color, pubmed-meshheading:17531583-Female, pubmed-meshheading:17531583-Follow-Up Studies, pubmed-meshheading:17531583-Heart Valve Prosthesis Implantation, pubmed-meshheading:17531583-Humans, pubmed-meshheading:17531583-Korea, pubmed-meshheading:17531583-Male, pubmed-meshheading:17531583-Middle Aged, pubmed-meshheading:17531583-Mitral Valve Insufficiency, pubmed-meshheading:17531583-Mitral Valve Stenosis, pubmed-meshheading:17531583-Multivariate Analysis, pubmed-meshheading:17531583-Proportional Hazards Models, pubmed-meshheading:17531583-Recurrence, pubmed-meshheading:17531583-Reoperation, pubmed-meshheading:17531583-Research Design, pubmed-meshheading:17531583-Retrospective Studies, pubmed-meshheading:17531583-Time Factors, pubmed-meshheading:17531583-Treatment Outcome
pubmed:year
2007
pubmed:articleTitle
Comparison of long-term outcome after mitral valve replacement or repeated balloon mitral valvotomy in patients with restenosis after previous balloon valvotomy.
pubmed:affiliation
Cardiology Division, Yonsei Cardiovascular Center and Cardiovascular Research Institute, Yonsei University College of Medicine, Seoul, South Korea.
pubmed:publicationType
Journal Article, Comparative Study