|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0004561,
umls-concept:C0021027,
umls-concept:C0022658,
umls-concept:C0025926,
umls-concept:C0026809,
umls-concept:C0030956,
umls-concept:C0042196,
umls-concept:C0376298,
umls-concept:C1513867,
umls-concept:C1545588,
umls-concept:C1861886
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|
pubmed:issue |
6
|
|
pubmed:dateCreated |
2007-6-14
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|
pubmed:abstractText |
Ig molecules contain epitopes that can induce T cell-mediated immune responses. B cells can process and present such epitopes and activate T cells. The purpose of the present study was to test our hypothesis that T cells that recognize an Ig consensus sequence presented by B cells will modulate lupus-like disease in mice.
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pubmed:grant |
|
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pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
AIM
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|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jun
|
|
pubmed:issn |
0004-3591
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
56
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
1945-53
|
|
pubmed:dateRevised |
2007-12-3
|
|
pubmed:meshHeading |
pubmed-meshheading:17530718-Animals,
pubmed-meshheading:17530718-Antibodies, Antinuclear,
pubmed-meshheading:17530718-Antigens, CD28,
pubmed-meshheading:17530718-B-Lymphocytes,
pubmed-meshheading:17530718-CD4-Positive T-Lymphocytes,
pubmed-meshheading:17530718-CD8-Positive T-Lymphocytes,
pubmed-meshheading:17530718-Consensus Sequence,
pubmed-meshheading:17530718-Epitopes, B-Lymphocyte,
pubmed-meshheading:17530718-Female,
pubmed-meshheading:17530718-Gene Transfer Techniques,
pubmed-meshheading:17530718-Immunoglobulin G,
pubmed-meshheading:17530718-Lupus Erythematosus, Systemic,
pubmed-meshheading:17530718-Lupus Nephritis,
pubmed-meshheading:17530718-Mice,
pubmed-meshheading:17530718-Mice, Inbred NZB,
pubmed-meshheading:17530718-Vaccination,
pubmed-meshheading:17530718-Vaccines
|
|
pubmed:year |
2007
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|
pubmed:articleTitle |
Protection against renal disease in (NZB x NZW)F(1) lupus-prone mice after somatic B cell gene vaccination with anti-DNA immunoglobulin consensus peptide.
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|
pubmed:affiliation |
David Geffen School of Medicine, University of California, Los Angeles, California, USA.
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|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
|
