Source:http://linkedlifedata.com/resource/pubmed/id/17524024
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
7
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pubmed:dateCreated |
2007-6-19
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pubmed:abstractText |
Polymorphisms of genes are transmitted together in haplotypes, which can be used in the study of the development of complex diseases such as respiratory distress syndrome (RDS). The surfactant proteins (SPs) play important roles in lung function, and genetic variants of these proteins have been linked with lung diseases, including RDS. To determine whether haplotypes of SP-A and SP-D are transmitted disproportionately from parents to offspring with RDS, we hypothesized that previously unstudied genetic haplotypes of these SP genes are associated with the development of RDS.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0803-5253
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
96
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
985-9
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pubmed:dateRevised |
2007-12-3
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pubmed:meshHeading |
pubmed-meshheading:17524024-Adult,
pubmed-meshheading:17524024-Child,
pubmed-meshheading:17524024-Family Health,
pubmed-meshheading:17524024-Female,
pubmed-meshheading:17524024-Genetic Markers,
pubmed-meshheading:17524024-Genetic Predisposition to Disease,
pubmed-meshheading:17524024-Haplotypes,
pubmed-meshheading:17524024-Humans,
pubmed-meshheading:17524024-Infant, Newborn,
pubmed-meshheading:17524024-Linkage Disequilibrium,
pubmed-meshheading:17524024-Male,
pubmed-meshheading:17524024-Polymorphism, Genetic,
pubmed-meshheading:17524024-Pulmonary Surfactant-Associated Protein A,
pubmed-meshheading:17524024-Pulmonary Surfactant-Associated Protein D,
pubmed-meshheading:17524024-Respiratory Distress Syndrome, Newborn
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pubmed:year |
2007
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pubmed:articleTitle |
Haplotypes of the surfactant protein genes A and D as susceptibility factors for the development of respiratory distress syndrome.
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pubmed:affiliation |
Department of Pediatrics, Penn State Children's Hospita, Pennsylvania State University College of Medicine, Hershey, Pennsylvania 17033, USA. nthomas@psu.edu
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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